Results 61 to 70 of about 1,789,995 (350)
Immunoglobulin Light Chains Control Permissiveness to Malignant B-Cell Transformation By RAS-Pathway Lesions [PDF]
, 2023 Lai N. Chan +5 more
openalex +1 more source
Particle In Cell Simulation of Combustion Synthesis of TiC Nanoparticles
, 2004 A coupled continuum-discrete numerical model is presented to study the synthesis of TiC nanosized aggregates during a self-propagating combustion synthesis (SHS) process. The overall model describes the transient of the basic mechanisms governing the SHS
Badhuri +23 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Thoracic Cancer, 2021 In advanced lung cancer treatment, immunotherapy provides durable responses in some patients. However, other patients experience progressive disease and the resistance mechanisms to immunotherapy have yet been fully elucidated.
Takuma Imakita +7 more
doaj +1 more source
HP-multigrid as smoother algorithm for higher order discontinuous Galerkin discretizations of advection dominated flows. Part II. Optimization of the Runge-Kutta smoother [PDF]
, 2011 Using a detailed multilevel analysis of the complete hp-Multigrid as Smoother algorithm accurate predictions are obtained of the spectral radius and operator norms of the multigrid error transformation operator.
Rhebergen, S., Vegt, J.J.W. van der
core +4 more sources
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Epicardial cell transformation
The FASEB Journal, 2010 The embryonic epicardium, which invests all the heart surface by midgestation, derives from an extracardiac progenitor tissue called the proepicardium. The embryonic epicardium gives rise to a population of mesenchymal cells called the epicardially‐derived cells (EPDCs) that populate the ...
openaire +1 more source
Neoplastic transformation of porcine mammary epithelial cells in vitro and tumor formation in vivo. [PDF]
, 2015 BackgroundThe mammary glands of pigs share many functional and morphological similarities with the breasts of humans, raising the potential of their utility for research into the mechanisms underlying normal mammary function and breast carcinogenesis ...
Borowsky, AD +5 more
core
Nanopipettes as Monitoring Probes for the Single Living Cell: State of the Art and Future Directions in Molecular Biology. [PDF]
, 2018 Examining the behavior of a single cell within its natural environment is valuable for understanding both the biological processes that control the function of cells and how injury or disease lead to pathological change of their function.
Bulbul, Gonca +4 more
core +2 more sources