Results 91 to 100 of about 5,097,355 (300)
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack +39 more
wiley +1 more source
Single cell electroporation on chip [PDF]
In this thesis the results of the development of microfluidic cell trap devices for single cell electroporation are described, which are to be used for gene transfection.
Valero, Ana
core +2 more sources
ABSTRACT Purpose Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods A multicenter retrospective review was performed
Hannah N. Rinehardt +76 more
wiley +1 more source
Cell-specific tools for understanding behavior
Novel tools that allow neuron-specific investigations of the structure controlling sleep regulation in fruit flies reveal the extent of neuronal heterogeneity.
Brandon L Holder, Stephane Dissel
doaj +1 more source
Understanding the principles governing neuronal diversity is a fundamental goal for neuroscience. Here, we provide an anatomical and transcriptomic database of nearly 200 genetically identified cell populations. By separately analyzing the robustness and
Ken Sugino +13 more
doaj +1 more source
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source
The 68,000-Dalton Neurofilament-Associated Polypeptide is a Component of Nonneuronal Cells and of Skeletal Myofibrils [PDF]
Purified preparations of 10-nm neurofilaments from rat spinal cord and bovine or porcine brain contain a predominant 68,000-dalton polypeptide. This polypeptide is also a major component of the neurofilaments that copurify with brain tubulin isolated by ...
Asai, David J. +2 more
core
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Juvenile Type Granulosa Cell Tumor
Abstract Granulosa cell tumor is a type of neoplasm, which represents 2-5% of all ovarian cancers. About 5% of these tumors are juvenile- type and usually occur to girls before puberty and to women younger than thirty years of age. There are signs premature puberty or premature emergence of secondary sexual characteristics with irregular
Andric B. +4 more
openaire +2 more sources
Bulk RNA-seq deconvolution heterogeneity across paired pancreatic cancer human samples
IntroductionThere is great promise in using genomic data to inform individual cancer treatment plans. Assessing intratumor genetic heterogeneity, studies have shown it may be possible to target biopsies to tumor subclones driving disease progression or ...
Rick J. Jansen +4 more
doaj +1 more source

