Results 71 to 80 of about 28,363,573 (344)

Single-cell nuclear architecture across cell types in the mouse brain

Science, 2021
Description Nuclear organization in the brain The brain consists of different cell types, neurons and glial cells, that have different nuclear architecture. Takei et al.
Yodai Takei, Shiwei Zheng, Jina Yun, Sheel Shah, N. Pierson, Jonathan White, Simon Schindler, Carsten H. Tischbirek, Guocheng Yuan, L. Cai   +9 more
semanticscholar   +1 more source

Extensive cellular multi-tasking within Bacillus subtilis biofilms

mSystems, 2023
Bacillus subtilis is a soil-dwelling bacterium that can form biofilms, or communities of cells surrounded by a self-produced extracellular matrix. In biofilms, genetically identical cells often exhibit heterogeneous transcriptional phenotypes, so that ...
Sarah M. Yannarell, Eric S. Beaudoin, Hunter S. Talley, Alexi A. Schoenborn, Galya Orr, Christopher R. Anderton, William B. Chrisler, Elizabeth A. Shank   +7 more
doaj   +1 more source

Why isn’t each cell its own cell type? Diminishing returns of increasing cell type diversity can explain cell type allometry

Frontiers in Cell and Developmental Biology, 2022
Since the discovery of cells by Robert Hooke and Antoni van Leeuwenhoek in the 17th century, thousands of different cell types have been identified, most recently by sequencing-based single-cell profiling techniques. Yet, for many organisms we still do not know, how many different cell types they are precisely composed of.
openaire   +3 more sources

Cell type-specific driver lines targeting the Drosophila central complex and their use to investigate neuropeptide expression and sleep regulation

eLife
The central complex (CX) plays a key role in many higher-order functions of the insect brain including navigation and activity regulation. Genetic tools for manipulating individual cell types, and knowledge of what neurotransmitters and neuromodulators ...
Tanya Wolff, Mark Eddison, Nan Chen, Aljoscha Nern, Preeti Sundaramurthi, Divya Sitaraman, Gerald M Rubin   +6 more
doaj   +1 more source

Understanding the mechanism of hepatic fibrosis and potential therapeutic approaches

The Saudi Journal of Gastroenterology, 2012
Hepatic fibrosis (HF) is a progressive condition with serious clinical complications arising from abnormal proliferation and amassing of tough fibrous scar tissue. This defiance of collagen fibers becomes fatal due to ultimate failure of liver functions.
Areeba Ahmad, Riaz Ahmad
doaj   +1 more source

Distinct Transcriptomic Cell Types and Neural Circuits of the Subiculum and Prosubiculum along the Dorsal-Ventral Axis

Cell Reports, 2020
Summary: Subicular regions play important roles in spatial processing and many cognitive functions, and these are mainly attributed to the subiculum (Sub) rather than the prosubiculum (PS).
Song-Lin Ding, Zizhen Yao, Karla E. Hirokawa, Thuc Nghi Nguyen, Lucas T. Graybuck, Olivia Fong, Phillip Bohn, Kiet Ngo, Kimberly A. Smith, Christof Koch, John W. Phillips, Ed S. Lein, Julie A. Harris, Bosiljka Tasic, Hongkui Zeng   +14 more
doaj   +1 more source

The Role of the Medial Septum—Associated Networks in Controlling Locomotion and Motivation to Move

Frontiers in Neural Circuits, 2021
The Medial Septum and diagonal Band of Broca (MSDB) was initially studied for its role in locomotion. However, the last several decades were focussed on its intriguing function in theta rhythm generation.
Petra Mocellin, Petra Mocellin, Sanja Mikulovic   +2 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Harnessing the power of cell transplantation to target respiratory dysfunction following spinal cord injury. [PDF]

, 2017
The therapeutic benefit of cell transplantation has been assessed in a host of central nervous system (CNS) diseases, including disorders of the spinal cord such as traumatic spinal cord injury (SCI).
Charsar, Brittany A., Lepore, Angelo C., Urban, Mark W.   +2 more
core   +2 more sources

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source