Results 51 to 60 of about 28,363,573 (344)
Automated computation of arbor densities: a step toward identifying neuronal cell types
Frontiers in Neuroanatomy, 2014 The shape and position of a neuron convey information regarding its molecular and functional identity. The identification of cell types from structure, a classic method, relies on the time-consuming step of arbor tracing.
Uygar eSümbül +7 more
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Quantitative analysis of cell types during growth and morphogenesis in Hydra [PDF]
, 1973 Tissue maceration was used to determine the absolute number and the distribution of cell types in Hydra. It was shown that the total number of cells per animal as well as the distribution of cells vary depending on temperature, feeding conditions, and ...
A. Gierer +16 more
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A Derived Positional Mapping of Inhibitory Subtypes in the Somatosensory Cortex
Frontiers in Neuroanatomy, 2019 Obtaining a catalog of cell types is a fundamental building block for understanding the brain. The ideal classification of cell-types is based on the profile of molecules expressed by a cell, in particular, the profile of genes expressed. One strategy is,
Daniel Keller +7 more
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Transcriptional landscape of epithelial and immune cell populations revealed through FACS-seq of healthy human skin. [PDF]
, 2017 Human skin consists of multiple cell types, including epithelial, immune, and stromal cells. Transcriptomic analyses have previously been performed from bulk skin samples or from epithelial and immune cells expanded in cell culture.
Ahn, Richard S +9 more
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Cell-type annotation with accurate unseen cell-type identification using multiple references
PLOS Computational Biology, 2022 The recent advances in single-cell RNA sequencing (scRNA-seq) techniques have stimulated efforts to identify and characterize the cellular composition of complex tissues. With the advent of various sequencing techniques, automated cell-type annotation using a well-annotated scRNA-seq reference becomes popular.
Yi-Xuan Xiong +3 more
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Cell types of origin of the cell-free transcriptome
Nature Biotechnology, 2022 Cell-free RNA from liquid biopsies can be analyzed to determine disease tissue of origin. We extend this concept to identify cell types of origin using the Tabula Sapiens transcriptomic cell atlas as well as individual tissue transcriptomic cell atlases ...
S. Vorperian +179 more
semanticscholar +1 more source
How Many Cell Types Are in the Kidney and What Do They Do?
Annual Review of Physiology, 2021 The kidney maintains electrolyte, water, and acid-base balance, eliminates foreign and waste compounds, regulates blood pressure, and secretes hormones. There are at least 16 different highly specialized epithelial cell types in the mammalian kidney. The
Michael S. Balzer +2 more
semanticscholar +1 more source
Frontiers in Neuroscience, 2013 An important goal in neuroscience is to understand gene expression patterns in the brain. The recent availability of comprehensive and detailed expression atlases for mouse and human creates opportunities to discover global patterns and perform cross ...
Powell Patrick Cheng Tan +5 more
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Oxidative Stress and the Neurovascular Unit
Life, 2021 The neurovascular unit (NVU) is a relatively recent concept that clearly describes the relationship between brain cells and their blood vessels. The components of the NVU, comprising different types of cells, are so interrelated and associated with each ...
Carmela Rinaldi +5 more
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Cell type prioritization in single-cell data [PDF]
Nature Biotechnology, 2019 We present a machine-learning method to prioritize the cell types most responsive to biological perturbations within high-dimensional single-cell data. We validate our method, Augur (https://github.com/neurorestore/Augur), on a compendium of single-cell RNA-seq, chromatin accessibility, and imaging transcriptomics datasets. We apply Augur to expose the
Michael A. Skinnider +13 more
openaire +3 more sources