Results 41 to 50 of about 28,363,573 (344)
eLife, 2019 Recent transcriptional profiling technologies are uncovering previously-undefined cell populations and molecular markers at an unprecedented pace. While single cell RNA (scRNA) sequencing is an attractive approach for unbiased transcriptional profiling ...
Ryoji Amamoto +7 more
doaj +1 more source
Morphological diversity of single neurons in molecularly defined cell types
Nature, 2021 Dendritic and axonal morphology reflects the input and output of neurons and is a defining feature of neuronal types1,2, yet our knowledge of its diversity remains limited.
Hanchuan Peng +77 more
semanticscholar +1 more source
A transcriptomic atlas of mouse cerebellar cortex comprehensively defines cell types
Nature, 2021 The cerebellar cortex is a well-studied brain structure with diverse roles in motor learning, coordination, cognition and autonomic regulation. However, a complete inventory of cerebellar cell types is currently lacking.
Velina Kozareva +9 more
semanticscholar +1 more source
A harmonized atlas of mouse spinal cord cell types and their spatial organization
Nature Communications, 2021 Single-cell RNA sequencing data can unveil the molecular diversity of cell types. Cell type atlases of the mouse spinal cord have been published in recent years but have not been integrated together.
D. Russ +10 more
semanticscholar +1 more source
A human lung tumor microenvironment interactome identifies clinically relevant cell-type cross-talk. [PDF]
, 2020 BackgroundTumors comprise a complex microenvironment of interacting malignant and stromal cell types. Much of our understanding of the tumor microenvironment comes from in vitro studies isolating the interactions between malignant cells and a single ...
Azizi, Armon +19 more
core +4 more sources
A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation
bioRxiv, 2020 The isocortex and hippocampal formation are two major structures in the mammalian brain that play critical roles in perception, cognition, emotion and learning. Both structures contain multiple regions, for many of which the cellular composition is still
Z. Yao +34 more
semanticscholar +1 more source
Immunomodulation—What to Modulate and Why? Potential Immune Targets
Frontiers in Dental Medicine, 2022 Despite over 50 years of research into the immunology of periodontal disease, the precise mechanisms and the role of many cell types remains an enigma. Progress has been limited by the inability to determine disease activity clinically. Understanding the
Su Sheng Quach +3 more
doaj +1 more source
Human Myoblast and Mesenchymal Stem Cell Interactions Visualized by Videomicroscopy. [PDF]
, 2015 Muscle-derived progenitor cell (myoblast) therapy has promise for the treatment of denervated, weakened, and fibrotic muscle. The best methods for injecting myoblasts to promote fusion and retention have yet to be determined, however.
Belafsky, Peter C +7 more
core +1 more source
Conserved cell types with divergent features in human versus mouse cortex
Nature, 2019 Elucidating the cellular architecture of the human cerebral cortex is central to understanding our cognitive abilities and susceptibility to disease. Here we used single-nucleus RNA-sequencing analysis to perform a comprehensive study of cell types in ...
R. Hodge +63 more
semanticscholar +1 more source
bioRxiv, 2020 The new coronavirus (2019-nCoV) outbreak from December 2019 in Wuhan, Hubei, China, has been declared a global public health emergency. Angiotensin I converting enzyme 2 (ACE2), is the host receptor by 2019-nCov to infect human cells.
Furong Qi +3 more
semanticscholar +1 more source