Results 61 to 70 of about 28,363,573 (344)
Journal of Inflammation Research, 2021 Xinwei Cao,1 Yajun Li,1 Jianrong Shi,2 Huifang Tang1 1Department of Pharmacology, School of Basic Medical Sciences, Zhejiang University, Hangzhou, 310058, People’s Republic of China; 2Department of Clinical Laboratory, Children’s Hospital ...
Cao X, Li Y, Shi J, Tang H
doaj
Biomolecules, 2023 The etiology of osteonecrosis of the femoral head (ONFH) is not yet fully understood. However, ONFH is a common disease with high morbidity, and approximately one-third of cases are caused by glucocorticoids.
Yingjie Wang +5 more
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Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate. [PDF]
, 2017 Adult stem cells commonly give rise to transit-amplifying progenitors, whose progeny differentiate into distinct cell types. It is unclear if stem cell niche signals coordinate fate decisions within the progenitor pool.
Burrous, Haley +4 more
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Navigating mouse cell types [PDF]
Nature Reviews Genetics, 2018 A new study reports the ‘Tabula Muris’, an atlas of single-cell RNA sequencing data from >100,000 cells across 20 mouse tissues.
openaire +2 more sources
Single-Cell Transcriptomes Reveal a Complex Cellular Landscape in the Middle Ear and Differential Capacities for Acute Response to Infection. [PDF]
, 2020 Single-cell transcriptomics was used to profile cells of the normal murine middle ear. Clustering analysis of 6770 transcriptomes identified 17 cell clusters corresponding to distinct cell types: five epithelial, three stromal, three lymphocyte, two ...
Draf, Clara +6 more
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Context-dependent signaling of coincident auditory and visual events in primary visual cortex
eLife, 2019 Detecting rapid, coincident changes across sensory modalities is essential for recognition of sudden threats or events. Using two-photon calcium imaging in identified cell types in awake, head-fixed mice, we show that, among the basic features of a sound
Thomas Deneux +5 more
doaj +1 more source
Predicting cell types and genetic variations contributing to disease by combining GWAS and epigenetic data [PDF]
, 2013 Genome-wide association studies (GWASs) identify single nucleotide polymorphisms (SNPs) that are enriched in individuals suffering from a given disease. Most disease-associated SNPs fall into non-coding regions, so that it is not straightforward to infer
A Milosavljevic +57 more
core +3 more sources
Molecular Oncology, 2020 Single‐cell transcriptomics have revolutionized our understanding of the cell composition of tumors and allowed us to identify new subtypes of cells. Despite rapid technological advancements, single‐cell analysis remains resource‐intense hampering the ...
Max Krämer +19 more
doaj +1 more source
Phylogenetic Analysis of Cell Types using Histone Modifications
, 2013 In cell differentiation, a cell of a less specialized type becomes one of a more specialized type, even though all cells have the same genome. Transcription factors and epigenetic marks like histone modifications can play a significant role in the ...
Bucher, Philipp +3 more
core +1 more source
Cellular deconvolution of GTEx tissues powers discovery of disease and cell-type associated regulatory variants. [PDF]
, 2020 The Genotype-Tissue Expression (GTEx) resource has provided insights into the regulatory impact of genetic variation on gene expression across human tissues; however, thus far has not considered how variation acts at the resolution of the different cell ...
D'Antonio, Matteo +3 more
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