Results 91 to 100 of about 28,363,573 (344)

Cellular taxonomy and spatial organization of the murine ventral posterior hypothalamus

eLife, 2020
The ventral posterior hypothalamus (VPH) is an anatomically complex brain region implicated in arousal, reproduction, energy balance, and memory processing.
Laura E Mickelsen, William F Flynn, Kristen Springer, Lydia Wilson, Eric J Beltrami, Mohan Bolisetty, Paul Robson, Alexander C Jackson   +7 more
doaj   +1 more source

Lineage dynamics of murine pancreatic development at single-cell resolution. [PDF]

, 2018
Organogenesis requires the complex interactions of multiple cell lineages that coordinate their expansion, differentiation, and maturation over time.
Byrnes, Lauren E, Gilchrist, Caroline L, Knox, Sarah M, Meyer, Nathaniel P, Sneddon, Julie B, Subramaniam, Meena, Tward, Aaron D, Wong, Daniel M, Ye, Chun J   +8 more
core   +2 more sources

stLearn: integrating spatial location, tissue morphology and gene expression to find cell types, cell-cell interactions and spatial trajectories within undissociated tissues

bioRxiv, 2020
Spatial Transcriptomics is an emerging technology that adds spatial dimensionality and tissue morphology to the genome-wide transcriptional profile of cells in an undissociated tissue.
D. Pham, Xiao Tan, Jun Xu, Laura F Grice, P. Lam, A. Raghubar, Jana Vukovic, M. Ruitenberg, Q. Nguyen   +8 more
semanticscholar   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Cell-type-specific neuroanatomy of cliques of autism-related genes in the mouse brain

Frontiers in Computational Neuroscience, 2015
Two cliques of genes identified computationally for their high co-expression in the mouse brain according to the Allen Brain Atlas, and for their enrichment in genes related to autism spectrum disorder, have recently been shown to be highly co ...
Pascal eGrange, Idan eMenashe, Mike eHawrylycz   +2 more
doaj   +1 more source

Interneuron-specific gamma synchronization indexes cue uncertainty and prediction errors in lateral prefrontal and anterior cingulate cortex

eLife, 2021
Inhibitory interneurons are believed to realize critical gating functions in cortical circuits, but it has been difficult to ascertain the content of gated information for well-characterized interneurons in primate cortex.
Kianoush Banaie Boroujeni, Paul Tiesinga, Thilo Womelsdorf   +2 more
doaj   +1 more source

RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types

Cell Reports, 2019
Summary The molecular characterization of immune subsets is important for designing effective strategies to understand and treat diseases. We characterized 29 immune cell types within the peripheral blood mononuclear cell (PBMC) fraction of healthy ...
G. Monaco, Bernett Lee, Weili Xu, Seri Mustafah, Y. Hwang, Christophe Carré, N. Burdin, Lucian Visan, M. Ceccarelli, M. Poidinger, A. Zippelius, João Pedro de Magalhães, A. Larbi   +12 more
semanticscholar   +1 more source

scCATCH: Automatic Annotation on Cell Types of Clusters from Single-Cell RNA Sequencing Data

iScience, 2020
Summary Recent advancements in single-cell RNA sequencing (scRNA-seq) have facilitated the classification of thousands of cells through transcriptome profiling, wherein accurate cell type identification is critical for mechanistic studies.
Xin Shao, J. Liao, Xiaoyan Lu, Rui Xue, Ni Ai, Xiaohui Fan   +5 more
semanticscholar   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

A mixed-cell propagation model for interference prediction in a UMTS network [PDF]

, 2001
With the support of mixed cells and hierarchical cell structures in UMTS, propagation information (coverage and interference) between different cell types is required.
Nix, AR, Tameh, EK
core   +2 more sources