Results 11 to 20 of about 5,097,355 (300)
Artificial-cell-type aware cell-type classification in CITE-seq [PDF]
Bioinformatics, 2020 Abstract Motivation Cellular Indexing of Transcriptomes and Epitopes by sequencing (CITE-seq), couples the measurement of surface marker proteins with simultaneous sequencing of mRNA at single cell level, which brings accurate cell surface phenotyping to single-cell transcriptomics ...
Lian, Qiuyu +6 more
openaire +2 more sources
Germ cells: ENCODE’s forgotten cell type
Biology of Reproduction, 2021 AbstractMore than a decade ago, the ENCODE and NIH Epigenomics Roadmap consortia organized large multilaboratory efforts to profile the epigenomes of >110 different mammalian somatic cell types. This generated valuable publicly accessible datasets that are being mined to reveal genome-wide patterns of a variety of different epigenetic parameters.
John R, McCarrey, Keren, Cheng
openaire +2 more sources
Single-cell RNA sequencing identifies distinct mouse medial ganglionic eminence cell types. [PDF]
, 2017 Many subtypes of cortical interneurons (CINs) are found in adult mouse cortices, but the mechanism generating their diversity remains elusive. We performed single-cell RNA sequencing on the mouse embryonic medial ganglionic eminence (MGE), the major ...
Chen, Ying-Jiun J +7 more
core +1 more source
Frontiers in Genetics, 2022 Osteosarcoma (OS) is a common bone cancer in children and adolescents, and metastasis and recurrence are the major causes of poor treatment outcomes. A better understanding of the tumor microenvironment is required to develop an effective treatment for ...
Ning Xu +6 more
doaj +1 more source
Cultured microvascular endothelial cells derived from the bovine corpus luteum possess NCAM-140 [PDF]
, 1992 Previously, five phenotypically different, stable types of microvascular endothelial cells (MVE) were isolated from the bovine corpus and cultured successfully. We found that three out of these five types of MVE express the neural cell adhesion molecule (
Caney +11 more
core +1 more source
Current Biology, 2004 For the first time in any substantially complex CNS structure, the inventory of cell types in the retina appears to be virtually complete. Evidence for this comes partly from a new, unbiased, morphological sampling technique; from the sheer volume of well-visualized cells that is easily generated by modern cell-filling methods; from the three ...
openaire +2 more sources
eLife, 2019 Recent transcriptional profiling technologies are uncovering previously-undefined cell populations and molecular markers at an unprecedented pace. While single cell RNA (scRNA) sequencing is an attractive approach for unbiased transcriptional profiling ...
Ryoji Amamoto +7 more
doaj +1 more source
Transcriptional landscape of epithelial and immune cell populations revealed through FACS-seq of healthy human skin. [PDF]
, 2017 Human skin consists of multiple cell types, including epithelial, immune, and stromal cells. Transcriptomic analyses have previously been performed from bulk skin samples or from epithelial and immune cells expanded in cell culture.
Ahn, Richard S +9 more
core +1 more source
The tailless Ortholog nhr-67 Regulates Patterning of Gene Expression and Morphogenesis in the C. elegans Vulva [PDF]
, 2007 Regulation of spatio-temporal gene expression in diverse cell and tissue types is a critical aspect of development. Progression through Caenorhabditis elegans vulval development leads to the generation of seven distinct vulval cell types (vulA, vulB1 ...
Fernandes, Jolene S., Sternberg, Paul W.
core +3 more sources
Immunomodulation—What to Modulate and Why? Potential Immune Targets
Frontiers in Dental Medicine, 2022 Despite over 50 years of research into the immunology of periodontal disease, the precise mechanisms and the role of many cell types remains an enigma. Progress has been limited by the inability to determine disease activity clinically. Understanding the
Su Sheng Quach +3 more
doaj +1 more source