Results 21 to 30 of about 5,097,355 (300)

Quantitative analysis of cell types during growth and morphogenesis in Hydra [PDF]

open access: yes, 1973
Tissue maceration was used to determine the absolute number and the distribution of cell types in Hydra. It was shown that the total number of cells per animal as well as the distribution of cells vary depending on temperature, feeding conditions, and ...
A. Gierer   +16 more
core   +1 more source

Automated computation of arbor densities: a step toward identifying neuronal cell types

open access: yesFrontiers in Neuroanatomy, 2014
The shape and position of a neuron convey information regarding its molecular and functional identity. The identification of cell types from structure, a classic method, relies on the time-consuming step of arbor tracing.
Uygar eSümbül   +7 more
doaj   +1 more source

Cis-regulatory basis of sister cell type divergence in the vertebrate retina [PDF]

open access: yes, 2019
Multicellular organisms evolved via repeated functional divergence of transcriptionally related sister cell types, but the mechanisms underlying sister cell type divergence are not well understood.
Corbo, Joseph C   +4 more
core   +3 more sources

A Derived Positional Mapping of Inhibitory Subtypes in the Somatosensory Cortex

open access: yesFrontiers in Neuroanatomy, 2019
Obtaining a catalog of cell types is a fundamental building block for understanding the brain. The ideal classification of cell-types is based on the profile of molecules expressed by a cell, in particular, the profile of genes expressed. One strategy is,
Daniel Keller   +7 more
doaj   +1 more source

Cornea organoids from human induced pluripotent stem cells. [PDF]

open access: yes, 2017
The cornea is the transparent outermost surface of the eye, consisting of a stratified epithelium, a collagenous stroma and an innermost single-cell layered endothelium and providing 2/3 of the refractive power of the eye. Multiple diseases of the cornea
Adams, Sheila M   +5 more
core   +3 more sources

Cell-type annotation with accurate unseen cell-type identification using multiple references

open access: yesPLOS Computational Biology, 2022
The recent advances in single-cell RNA sequencing (scRNA-seq) techniques have stimulated efforts to identify and characterize the cellular composition of complex tissues. With the advent of various sequencing techniques, automated cell-type annotation using a well-annotated scRNA-seq reference becomes popular.
Yi-Xuan Xiong   +3 more
openaire   +3 more sources

Neuron-enriched gene expression patterns are regionally anti-correlated with oligodendrocyte-enriched patterns in the adult mouse and human brain

open access: yesFrontiers in Neuroscience, 2013
An important goal in neuroscience is to understand gene expression patterns in the brain. The recent availability of comprehensive and detailed expression atlases for mouse and human creates opportunities to discover global patterns and perform cross ...
Powell Patrick Cheng Tan   +5 more
doaj   +1 more source

Oxidative Stress and the Neurovascular Unit

open access: yesLife, 2021
The neurovascular unit (NVU) is a relatively recent concept that clearly describes the relationship between brain cells and their blood vessels. The components of the NVU, comprising different types of cells, are so interrelated and associated with each ...
Carmela Rinaldi   +5 more
doaj   +1 more source

Cell type prioritization in single-cell data [PDF]

open access: yesNature Biotechnology, 2019
We present a machine-learning method to prioritize the cell types most responsive to biological perturbations within high-dimensional single-cell data. We validate our method, Augur (https://github.com/neurorestore/Augur), on a compendium of single-cell RNA-seq, chromatin accessibility, and imaging transcriptomics datasets. We apply Augur to expose the
Michael A. Skinnider   +13 more
openaire   +3 more sources

The Potentially Therapeutic Role of EPAC in Curbing the Process of Idiopathic Pulmonary Fibrosis via Differential Cellular Pathways

open access: yesJournal of Inflammation Research, 2021
Xinwei Cao,1 Yajun Li,1 Jianrong Shi,2 Huifang Tang1 1Department of Pharmacology, School of Basic Medical Sciences, Zhejiang University, Hangzhou, 310058, People’s Republic of China; 2Department of Clinical Laboratory, Children’s Hospital ...
Cao X, Li Y, Shi J, Tang H
doaj  

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