Results 11 to 20 of about 28,363,573 (344)

Distribution and Levels of Insulin-like Growth Factor 2 Receptor Across Mouse Brain Cell Types [PDF]

Receptors
Background: The insulin-like growth factor 2 receptor (IGF-2R), also known as the cation-independent mannose 6-phosphate receptor (CI-M6PR), is emerging as a critical receptor for brain function and disease. IGF-2R, in fact, plays a key role in long-term
Jessica R. Gaunt, Gokul Manoj, Cristina M. Alberini   +2 more
doaj   +2 more sources

Multimodal Analysis of Cell Types in a Hypothalamic Node Controlling Social Behavior.

Cell, 2019
The ventrolateral subdivision of the ventromedial hypothalamus (VMHvl) contains ∼4,000 neurons that project to multiple targets and control innate social behaviors including aggression and mounting.
Dong-Wook Kim, Z. Yao, Lucas T. Graybuck, Tae Kyung Kim, T. Nguyen, Kimberly A. Smith, Olivia Fong, Lynn Yi, N. Koulena, N. Pierson, Sheel Shah, Liching Lo, Allan-Hermann Pool, Yuki Oka, L. Pachter, L. Cai, Bosiljka Tasic, Hongkui Zeng, D. Anderson   +18 more
semanticscholar   +3 more sources

Shared and distinct transcriptomic cell types across neocortical areas

Nature, 2018
Bosiljka Tasic, Z. Yao, Lucas T. Graybuck, Kimberly A. Smith, T. Nguyen, Darren Bertagnolli, Jeff Goldy, E. Garren, M. Economo, Sarada Viswanathan, Osnat Penn, Trygve E Bakken, V. Menon, Jeremy A. Miller, Olivia Fong, Karla E. Hirokawa, K. Lathia, Christine Rimorin, Michael Tieu, Rachael Larsen, Tamara Casper, Eliza R. Barkan, Matthew Kroll, Sheana E. Parry, N. Shapovalova, Daniel Hirschstein, Julie Pendergraft, H. Sullivan, Tae Kyung Kim, A. Szafer, N. Dee, Peter A. Groblewski, Ian R. Wickersham, Ali H. Cetin, Julie A. Harris, Boaz P. Levi, S. Sunkin, L. Madisen, T. Daigle, L. Looger, Amy Bernard, John W. Phillips, E. Lein, M. Hawrylycz, K. Svoboda, Allan R. Jones, C. Koch, Hongkui Zeng   +47 more
semanticscholar   +3 more sources

A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain

bioRxiv, 2023
The mammalian brain is composed of millions to billions of cells that are organized into numerous cell types with specific spatial distribution patterns and structural and functional properties.
Z. Yao, Cindy T. J. van Velthoven, Michael Kunst, Meng Zhang, D. McMillen, Changkyu Lee, Won Jung, Jeff Goldy, Aliya Abdelhak, Pamela Baker, Eliza R. Barkan, Darren Bertagnolli, Jazmin Campos, Daniel Carey, Tamara Casper, A. Chakka, Rushil Chakrabarty, Sakshi Chavan, Min Chen, Michael Clark, Jennie L. Close, Kirsten Crichton, S. Daniel, Tim Dolbeare, Lauren Ellingwood, James Gee, Alexandra Glandon, Jessica Gloe, Joshua Gould, James Gray, Nathan Guilford, Junitta B. Guzman, Daniel Hirschstein, Windy V. Ho, Kelly Jin, Matthew Kroll, K. Lathia, Arielle Leon, Brian R. Long, Zoe Maltzer, Naomi Martin, Rachel McCue, Emma Meyerdierks, T. Nguyen, Trangthanh Pham, Christine Rimorin, Augustin Ruiz, N. Shapovalova, C. Slaughterbeck, J. Sulc, Michael Tieu, A. Torkelson, Herman Tung, N. V. Cuevas, Katherine Wadhwani, Katelyn Ward, Boaz P. Levi, Colin Farrell, C. Thompson, S. Mufti, Chelsea M. Pagan, Lauren Kruse, N. Dee, S. Sunkin, Luke Esposito, M. Hawrylycz, Jack Waters, Lydia Ng, Kimberly A. Smith, Bosiljka Tasic, X. Zhuang, Hongkui Zeng   +71 more
semanticscholar   +2 more sources

Artificial-cell-type aware cell-type classification in CITE-seq [PDF]

Bioinformatics, 2020
Abstract Motivation Cellular Indexing of Transcriptomes and Epitopes by sequencing (CITE-seq), couples the measurement of surface marker proteins with simultaneous sequencing of mRNA at single cell level, which brings accurate cell surface phenotyping to single-cell transcriptomics ...
Lian, Qiuyu, Xin, Hongyi, Ma, Jianzhu, Konnikova, Liza, Chen, Wei, Gu, Jin, Chen, Kong   +6 more
openaire   +2 more sources

A DNA methylation atlas of normal human cell types

Nature, 2023
DNA methylation is a fundamental epigenetic mark that governs gene expression and chromatin organization, thus providing a window into cellular identity and developmental processes^ 1 .
Netanel Loyfer, J. Magenheim, A. Peretz, G. Cann, J. Bredno, A. Klochendler, Ilana Fox-Fisher, Sapir Shabi-Porat, M. Hecht, Tsuria Pelet, J. Moss, Zeina Drawshy, Hamed Amini, P. Moradi, Sudharani Nagaraju, D. Bauman, D. Shveiky, S. Porat, U. Dior, G. Rivkin, O. Or, N. Hirshoren, E. Carmon, A. Pikarsky, A. Khalaileh, G. Zamir, R. Grinbaum, Machmud Abu Gazala, I. Mizrahi, N. Shussman, A. Korach, O. Wald, U. Izhar, E. Erez, V. Yutkin, Yaacov Samet, Devorah Rotnemer Golinkin, K. Spalding, H. Druid, P. Arner, A. Shapiro, M. Grompe, Alex Aravanis, O. Venn, A. Jamshidi, R. Shemer, Y. Dor, Benjamin Glaser, Tommy Kaplan   +48 more
semanticscholar   +1 more source

Transcriptomic diversity of cell types across the adult human brain

bioRxiv, 2022
The human brain directs a wide range of complex behaviors ranging from fine motor skills to abstract intelligence and emotion. However, the diversity of cell types that support these skills has not been fully described.
K. Siletti, R. Hodge, Alejandro Mossi Albiach, Lijuan Hu, K. Lee, P. Lönnerberg, Trygve E Bakken, S. Ding, Michael Clark, Tamara Casper, N. Dee, Jessica Gloe, C. Keene, J. Nyhus, Herman Tung, A. Yanny, E. Arenas, E. Lein, S. Linnarsson   +18 more
semanticscholar   +1 more source

Rostral and caudal basolateral amygdala engage distinct circuits in the prelimbic and infralimbic prefrontal cortex

eLife, 2022
Connections from the basolateral amygdala (BLA) to medial prefrontal cortex (PFC) regulate memory and emotion and become disrupted in neuropsychiatric disorders.
Kasra Manoocheri, Adam G Carter
doaj   +1 more source

Germ cells: ENCODE’s forgotten cell type

Biology of Reproduction, 2021
AbstractMore than a decade ago, the ENCODE and NIH Epigenomics Roadmap consortia organized large multilaboratory efforts to profile the epigenomes of >110 different mammalian somatic cell types. This generated valuable publicly accessible datasets that are being mined to reveal genome-wide patterns of a variety of different epigenetic parameters.
John R, McCarrey, Keren, Cheng
openaire   +2 more sources

Whole animal freeze-fracture scanning electron microscopy: an easy-to-use method to investigate cell type morphology of marine embryos and larvae

Frontiers in Ecology and Evolution, 2023
Morphological and molecular characterization of cell types, organs and individual organisms is essential for understanding the origins of morphogenesis.
Periklis Paganos, Filomena Caccavale, Maria Cocurullo, Enrico D’Aniello, Maria Ina Arnone, Giovanna Benvenuto   +5 more
doaj   +1 more source