Results 91 to 100 of about 1,019,407 (314)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Transcriptional activity around bacterial cell death reveals molecular biomarkers for cell viability
, 2008 Background In bacteriology, the ability to grow in selective media and to form colonies on nutrient agar plates is routinely used as a retrospective criterion for the detection of living bacteria.
Schuren Frank H +15 more
core +1 more source
مجلة بغداد للعلومThis in vivo study is aimed to assess the antibiofilm and cytotoxic potential of selected microalgae isolates. Different concentration of microalgal isolates used for each of antibiofilm and cytotoxic studies.
Sewgil Saaduldeen Anwer +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Biotechnological Potential of Isolated Bacteria from Post-Consumer LED Lamps for Solubilization of Critical Metals [PDF]
Materials ResearchThis study evaluates the biotechnological potential of isolated microorganisms for the solubilization of critical and valuable metals in LED lamp waste through a biometallurgical process, called bioleaching or biomineration, which occurs with the ...
Isabela Natália da Silva Ferreira +8 more
doaj +1 more source
Defining viability in mammalian cell cultures
Biotechnology Letters, 2011 A large number of assays are available to monitor viability in mammalian cell cultures with most defining loss of viability as a loss of plasma membrane integrity, a characteristic of necrotic cell death. However, the majority of cultured cells die by apoptosis and early apoptotic cells, although non-viable, maintain an intact plasma membrane and are ...
Browne, Susan M., Al-Rubeai, Mohamed
openaire +3 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The dihydroceramide desaturase is not essential for cell viability in Schizosaccharomyces pombe
, 2003 Recent studies have identified a new family of desaturase-like polypeptide sequences in many higher eukaryotes. Functional characterisation of one member of this family, from Schizosaccharomyces pombe, revealed the enzyme to be a sphingolipid desaturase.
Beale, Michael H. +14 more
core +1 more source
Viability of exfoliated colorectal carcinoma cells
Journal of British Surgery, 1984 Abstract The viability of tumour cells shed into the intestinal lumen was determined in 49 patients with carcinoma of the large bowel. Preoperative colorectal lavage was performed in 19 patients and irrigation of the cut ends of the operative specimen in 30 patients.
H C, Umpleby +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source