Results 81 to 90 of about 5,277,948 (253)

Improvement in the Viability of Cryopreserved Cells by Microencapsulation.

TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series B, 2001
The purpose of this study is to clarify whether microencapsulated cells have an advantage over suspended cells in cryopreservation. Rat pheochromocytoma (CP 12) cells were selected for test biological cell and microencapusulated in alginate-polylysine-alginate membranes.
MATSUMOTO, Yoshifumi, MORINAGA, Yukihiro, UJIHIRA, Masanobu, OKA, Kotaro, TANISHITA, Kazuo   +4 more
openaire   +3 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Agriculture Viability Grants Program [application] 2016.

, 2016
Annual; "Farm Viability Grant, Farm Transition Grant."; Funding for the State of Connecticut agriculture viability grants was established in 2005 through Public Act 05-228, an Act Concerning Farm Land Preservation, Land Protection, Affordable Housing and
Agriculture Viability Grants Program (Conn.)
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Exploring the hepatoprotective properties of citronellol: In vitro and in silico studies on ethanol-induced damage in HepG2 cells

Open Life Sciences
Citronellol (CT) is a monoterpene alcohol present in the essential oil of plants of the genus Cymbopogon and exhibits diverse pharmacological activities. The aim of the current study was to investigate the hepatoprotective potential of CT against ethanol-
Malik Muhammad Nasir Hayat, Abid Iqra, Ismail Sana, Anjum Irfan, Qadir Halima, Maqbool Tahir, Najam Komal, Ibenmoussa Samir, Bourhia Mohammed, Salamatullah Ahmad Mohammad, Wondmie Gezahign Fentahun   +10 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Agriculture Viability Grants Program : [application] 2017.

, 2017
Annual; "Farm Viability Grant, Farm Transition Grant."; Funding for the State of Connecticut agriculture viability grants was established in 2005 through Public Act 05-228, an Act Concerning Farm Land Preservation, Land Protection, Affordable Housing and
Agriculture Viability Grants Program (Conn.)
core   +1 more source

VIABILITY OF DETACHED ROOT–CAP CELLS

American Journal of Botany, 1919
One can find in various texts the statement that the root-cap cells of plants die and are sloughed off, and it is probably the general opinion among botanists that the root-cap cells are either dead when they are sloughed off or that they die soon thereafter. Thus, in Jost's Plant Physiology (translation by Gibson, p. 283) the statements concerning the
openaire   +3 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Tube-forming device design for the creation of cell-integrated alginate tubes [PDF]

, 2008
This thesis describes a generic system capable of forming cell-populated alginate tubes either by seeding cells within its lumen, or integrating cells within the tube walls.
Chau, G K, Chau, G.K.
core