Results 191 to 200 of about 15,438,001 (312)

Cell volume controlled by LRRC8A-formed volume-regulated anion channels fine-tunes T cell activation and function. [PDF]

Nat Commun, 2023
Wang Y, Sun Z, Ping J, Tang J, He B, Chang T, Zhou Q, Yuan S, Tang Z, Li X, Lu Y, He R, He X, Liu Z, Yin L, Wu N.   +15 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

An optimized protocol for efficient derivation of pancreatic islets from multiple human pluripotent stem cell lines

The success of cell therapy for type 1 diabetes (T1D) depends on reliable differentiation of stem cells into functional pancreatic islets. Current protocols produce stem cell-derived islets (SC-islets) that contain non-endocrine cells and show limited ...
Efstathopoulos, Paschalis, Bryzgalova, Galyna, Zhao, Cheng, Lanner, Fredrik, Blust, Kelly, Hedhammar, My, Wu, Siqin, Berggren, Per Olof, Falk, Anna, Erbil, Eda, Chandel, Shivam, Efstathopoulos, P, Bryzgalova, Galyna,, Falk, A,, Falk, Anna,, Zhao, C,, Erbil, E, Berggren, Per Olof,, Zhao, Cheng,, Lanner, Fredrik,, Blust, Kelly,, Hedhammar, M, Bryzgalova, G,, Wu, S, Berggren, P-O, Wu, Siqin,, Chandel, S,, Hedhammar, My,, Blust, K, Chandel, Shivam,, Erbil, Eda,, Efstathopoulos, Paschalis,, Lund University.   +32 more
core   +1 more source

Disruption of macrophage cell volume drives inflammatory responses and type I interferon signaling. [PDF]

J Cell Biol
Cook JR, Gleeson TA, Gago S, Allan SM, Couper KN, Lawrence CB, Brough D, Green JP.   +7 more
europepmc   +1 more source

Tick-borne Pathogen Detection and Its Association with Alterations in Packed Cell Volume of Dairy Cattle in Thailand. [PDF]

Animals (Basel), 2023
Adjou Moumouni PF, Galon EM, Tumwebaze MA, Byamukama B, Ngasaman R, Tiwananthagorn S, Kamyingkird K, Inpankaew T, Xuan X.   +8 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Total blood volume and red blood cell volume are not associated with orthostatic intolerance in adults with myalgic encephalomyelitis/chronic fatigue syndrome. [PDF]

Physiol Rep
Yamazaki T, Mancini DM, Blate M, Quan P, Norweg A, Cook DB, Natelson BH.   +6 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

An ancestral glutamate receptor mediates cell volume regulation during high K⁺ stress in cyanobacteria. [PDF]

J Biol Chem
Zhang H, Tsujii M, Tanudjaja E, Shimizukawa H, Muraoka Y, Sato Y, Kera K, Furuta T, Kaneko S, Amaya S, Sugiura H, Arai F, Ishimaru Y, Uozumi N.   +13 more
europepmc   +1 more source