Results 21 to 30 of about 96,711 (247)

The cell cycle, autophagy, and cell wall integrity pathway jointly governed by MoSwe1 in Magnaporthe oryzae. [PDF]

Cell Commun Signal
AbstractThe cell cycle is pivotal to cellular differentiation in plant pathogenic fungi. Cell wall integrity (CWI) signaling plays an essential role in coping with cell wall stress. Autophagy is a degradation process in which cells decompose their components to recover macromolecules and provide energy under stress conditions.
Li L, Zhu XM, Bao JD, Wang JY, Liu XH, Lin FC.   +5 more
europepmc   +4 more sources

Involvement of the Cell Wall Integrity Pathway of Saccharomyces cerevisiae in Protection against Cadmium and Arsenate Stresses. [PDF]

Appl Environ Microbiol, 2020
Environmental pollution by metal/metalloids such as cadmium and arsenic has become a serious problem in many countries, especially in developing countries. This study shows that in the yeast S. cerevisiae , the CWI pathway plays a protective role against cadmium and arsenate through the upregulation of genes ...
Techo T, Charoenpuntaweesin S, Auesukaree C.   +2 more
europepmc   +4 more sources

Crosstalk between the calcineurin and cell wall integrity pathways prevents chitin overexpression in Candida albicans [PDF]

Journal of Cell Science, 2021
ABSTRACT Echinocandins such as caspofungin are frontline antifungal drugs that compromise β-1,3 glucan synthesis in the cell wall. Recent reports have shown that fungal cells can resist killing by caspofungin by upregulation of chitin synthesis, thereby sustaining cell wall integrity (CWI).
Alessandra da Silva Dantas, Filomena Nogueira, Keunsook K. Lee, Louise A. Walker, Matt Edmondson, Alexandra C. Brand, Megan D. Lenardon, Neil A. R. Gow   +7 more
openaire   +3 more sources

Cell Wall Integrity MAPK Pathway Is Essential for Lipid Homeostasis [PDF]

Journal of Biological Chemistry, 2008
The highly conserved yeast cell wall integrity mitogen-activated protein kinase pathway regulates cellular responses to cell wall and membrane stress. We report that this pathway is activated and essential for viability under growth conditions that alter both the abundance and pattern of synthesis and turnover of membrane phospholipids, particularly ...
Lilia R, Nunez, Stephen A, Jesch, Maria L, Gaspar, Claudia, Almaguer, Manuel, Villa-Garcia, Monica, Ruiz-Noriega, Jana, Patton-Vogt, Susan A, Henry   +7 more
openaire   +2 more sources

The RALF signaling pathway regulates cell wall integrity during pollen tube growth in maize

The Plant Cell, 2023
Abstract Autocrine signaling pathways regulated by RAPID ALKALINIZATION FACTORs (RALFs) control cell wall integrity during pollen tube germination and growth in Arabidopsis (Arabidopsis thaliana). To investigate the role of pollen-specific RALFs in another plant species, we combined gene expression data with phylogenetic and ...
Liang-Zi Zhou, Lele Wang, Xia Chen, Zengxiang Ge, Julia Mergner, Xingli Li, Bernhard Küster, Gernot Längst, Li-Jia Qu, Thomas Dresselhaus   +9 more
openaire   +3 more sources

Inactivating the mannose-ethanolamine phosphotransferase Gpi7 confers caspofungin resistance in the human fungal pathogen Candida albicans

The Cell Surface, 2021
Understanding the molecular mechanisms governing antifungal resistance is crucial for identifying new cellular targets for developing new antifungal therapeutics.
Guisheng Zeng, Xiaoli Xu, Jiaxin Gao, Alessandra da Silva Dantas, Neil A.R. Gow, Yue Wang   +5 more
doaj   +1 more source

The Role of the Cell Integrity Pathway in Septum Assembly in Yeast

Journal of Fungi, 2021
Cytokinesis divides a mother cell into two daughter cells at the end of each cell cycle and proceeds via the assembly and constriction of a contractile actomyosin ring (CAR).
Cesar Roncero, Rubén Celador, Noelia Sánchez, Patricia García, Yolanda Sánchez   +4 more
doaj   +1 more source

A seven-membered cell wall related transglycosylase gene family in Aspergillus niger is relevant for cell wall integrity in cell wall mutants with reduced α-glucan or galactomannan

The Cell Surface, 2020
Chitin is an important fungal cell wall component that is cross-linked to β-glucan for structural integrity. Acquisition of chitin to glucan cross-links has previously been shown to be performed by transglycosylation enzymes in Saccharomyces cerevisiae ...
Tim M. van Leeuwe, Jasper Wattjes, Anna Niehues, Gabriel Forn-Cuní, Nicholas Geoffrion, Hugo Mélida, Mark Arentshorst, Antonio Molina, Adrian Tsang, Annemarie H. Meijer, Bruno M. Moerschbacher, Peter J. Punt, Arthur F.J. Ram   +12 more
doaj   +1 more source

Roles of High Osmolarity Glycerol and Cell Wall Integrity Pathways in Cadmium Toxicity in Saccharomyces cerevisiae [PDF]

International Journal of Molecular Sciences, 2021
Cadmium is a carcinogen that can induce ER stress, DNA damage, oxidative stress and cell death. The yeast mitogen-activated protein kinase (MAPK) signalling pathways paly crucial roles in response to various stresses. Here, we demonstrate that the unfolded protein response (UPR) pathway, the high osmolarity glycerol (HOG) pathway and the cell wall ...
Yunying Zhao, Shiyun Li, Jing Wang, Yingli Liu, Yu Deng   +4 more
openaire   +2 more sources

Differential Requirement for the Cell Wall Integrity Sensor Wsc1p in Diploids Versus Haploids

Journal of Fungi, 2021
The primary role of the Cell Wall Integrity Pathway (CWI) in Saccharomyces cerevisiae is monitoring the state of the cell wall in response to general life cycle stresses (growth and mating) and imposed stresses (temperature changes and chemicals). Of the
Allison E. Hall, Miriam Lisci, Mark D. Rose   +2 more
doaj   +1 more source