Results 121 to 130 of about 2,959,069 (338)

A modelling approach towards Epidermal homoeostasis control

, 2007
In order to grasp the features arising from cellular discreteness and individuality, in large parts of cell tissue modelling agent-based models are favoured.
Barthel, Bashir, Bauer, Benoit, Bettelheim, Brilliantov, Byrne, Carvalho, Chenevert, Chu, Cickovski, Dallon, Dormann, Drasdo, Drasdo, Edelsbrunner, Ferreira, Fletcher, Freyer, Freyer, Galle, Galle, Gardner, Gatenby, Gernot Schaller, Gershenfeld, Graner, Hertz, Hoath, Johnson, Johnson, Joos, Kasting, Kreft, Kreft, Kreft, Landau, Livingston, Louzoun, Mahaffy, Maniotis, Meineke, Meyer-Hermann, Michael Meyer-Hermann, Montagna, Moy, Newman, Norlen, Picioreanu, Potten, Press, Savill, Schaller, Schaller, Schaller, Schwindt, Smolle, Tang, Tuchin, Turner, Verdier, von Neumann, Wehrle, Weliky, Weliky   +64 more
core   +1 more source

Oxidative stress in the pathogenesis of systemic scleroderma: An overview [PDF]

, 2018
Systemic sclerosis (SSc) is a rare disorder of the connective tissue characterized by fibrosis of the skin, skeletal muscles and visceral organs. Additional manifestations include activation of the immune system and vascular injury. SSc causes disability
Gambardella, Lucrezia, Giovannetti, Antonello, Malorni, Walter, Pietraforte, Donatella, Straface, Elisabetta, Vona, Rosa   +5 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Preliminary evaluation of adherence on abiotic and cellular surfaces of Acinetobacter baumannii strains isolated from catheter tips

Brazilian Journal of Infectious Diseases
The cell surface hydrophobicity and adhesion to abiotic and cellular surfaces was tested in five clinical strains of Acinetobacter baumannii isolated from catheter tips.
Gislaine Franco de Moura Costa, Maria Cristina Bronharo Tognim, Celso Luíz Cardoso, Floristher Elaine Carrara-Marrone, Lourdes Botelho Garcia   +4 more
doaj   +1 more source

Requirement of the NPXY motif in the integrin beta 3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo. [PDF]

, 1995
The NPXY sequence is highly conserved among integrin beta subunit cytoplasmic tails, suggesting that it plays a fundamental role in regulating integrin-mediated function.
Brooks, PC, Cheresh, DA, Damsky, C, Deming, SL, Filardo, EJ   +4 more
core   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

The relationship between cellular adhesion and surface roughness in polystyrene modified by microwave plasma radiation

International Journal of Nanomedicine, 2011
Esmaeil Biazar1, Majid Heidari2, Azadeh Asefnezhad2, Naser Montazeri11Department of Chemistry, Islamic Azad University, Tonekabon Branch, Mazandaran; 2Department of Biomaterial Engineering, Faculty of Biomedical Engineering, Science and Research Branch ...
Biazar E, Heidari M, Asfnezhad A, Montazeri N   +3 more
doaj  

Epithelial cell chirality emerges through the dynamic concentric pattern of actomyosin cytoskeleton

eLife
The chirality of tissues and organs is essential for their proper function and development. Tissue-level chirality derives from the chirality of individual cells that comprise the tissue, and cellular chirality is considered to emerge through the ...
Takaki Yamamoto, Tomoki Ishibashi, Yuko Mimori-Kiyosue, Sylvain Hiver, Naoko Tokushige, Mitsusuke Tarama, Masatoshi Takeichi, Tatsuo Shibata   +7 more
doaj   +1 more source

Determining cellular and biochemical function of a novel adhesion molecule in kidneys. [PDF]

, 2016
Acute kidney injury is an abrupt loss of kidney function that develops in short time with limited effective treatments other than kidney transplantation. We have identified TMIGD1 (Transmembrane immuno- globulin domain 1) as a novel receptor expressed in
Arafa, Emad
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source