Results 11 to 20 of about 216,120 (296)
Role of Membrane Biophysics in Alzheimer's - related cell pathways [PDF]
Frontiers in Neuroscience, 2015 Cellular membrane alterations are commonly observed in many diseases, including Alzheimer’s disease (AD). Membrane biophysical properties, such as membrane molecular order, membrane fluidity, organization of lipid rafts, and adhesion between membrane and
Donghui eZhu +5 more
doaj +9 more sources
Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs. [PDF]
, 2020 Cation-chloride-cotransporters (CCCs) catalyze transport of Cl- with K+ and/or Na+across cellular membranes. CCCs play roles in cellular volume regulation, neural development and function, audition, regulation of blood pressure, and renal function.
Brohawn, Stephen Graf +2 more
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FRET sensors reveal the retinal entry pathway in the G protein-coupled receptor rhodopsin
iScience, 2022 Summary: The photoreceptor rhodopsin (Rho) becomes active when a tethered inverse agonist ligand (11CR) is photoconverted to an agonist (ATR). The ligand-binding pocket of inactive rhodopsin is completely enclosed, whereas active rhodopsin displays pores
He Tian +4 more
doaj +1 more source
Biophysical Tools to Study Cellular Mechanotransduction [PDF]
Bioengineering, 2017 The cell membrane is the interface that volumetrically isolates cellular components from the cell’s environment. Proteins embedded within and on the membrane have varied biological functions: reception of external biochemical signals, as membrane channels, amplification and regulation of chemical signals through secondary messenger molecules ...
Muhamed, Ismaeel +2 more
openaire +4 more sources
Scientific Reports, 2021 In recent years’ synthesis of metal nanoparticle using plants has been extensively studied and recognized as a non-toxic and efficient method applicable in biomedical field.
Enerelt Urnukhsaikhan +4 more
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Metabolomic profiling of ZrO2 nanoparticles in MC3T3‐E1 cells
IET Nanobiotechnology, 2021 The authors' previous study showed that zirconium oxide nanoparticles (ZrO2 NPs) induce toxic effects in MC3T3‐E1 cells; however, its toxicological mechanism is still unclear.
Mingfu Ye +3 more
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A perspective on cortical layering and layer-spanning neuronal elements [PDF]
, 2018 This review article addresses the function of the layers of the cerebral cortex. We develop the perspective that cortical layering needs to be understood in terms of its functional anatomy, i.e., the terminations of synaptic inputs on distinct cellular ...
Larkum, Matthew E. +3 more
core +2 more sources
iScience, 2022 Summary: Cholesterol is a major regulator of multiple types of ion channels. Although there is increasing information about cholesterol binding sites, the molecular mechanisms through which cholesterol binding alters channel function are virtually ...
Nicolas Barbera +8 more
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Cell Reports, 2016 Release site clearance is an important process during synaptic vesicle (SV) recycling. However, little is known about its molecular mechanism. Here we identify self-assembly of exocytosed Synaptobrevin 2 (Syb2) and Synaptophysin 1 (Syp1) by homo- and ...
Rajit Rajappa +4 more
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In vitro assembly, positioning and contraction of a division ring in minimal cells
Nature Communications, 2022 Constructing a minimal protein machinery for self-division of membrane compartments is a major goal of bottom-up synthetic biology. Here, authors achieved the assembly, placement and onset of contraction of a minimal division ring in lipid vesicles.
Shunshi Kohyama +2 more
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