Results 1 to 10 of about 1,059,748 (164)
The Innate Cellular Immune Response in Xenotransplantation
Frontiers in Immunology, 2022 Xenotransplantation is very attractive strategy for addressing the shortage of donors. While hyper acute rejection (HAR) caused by natural antibodies and complement has been well defined, this is not the case for innate cellular xenogeneic rejection.
Akira Maeda +14 more
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Frontiers in Immunology, 2023 BackgroundEvidence has demonstrated inferior humoral immune responses after SARS-CoV-2 vaccination in kidney transplant recipients compared to the general population. However, data on cellular immune responses in this population have not been established.
Suwasin Udomkarnjananun +8 more
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CKD-related impairment in humoral and cellular immune response and potential correlation with long COVID-19: a systematic review [PDF]
Frontiers in ImmunologyIntroductionPatients with chronic kidney disease (CKD) are at high risk of morbidity and mortality from SARS-CoV-2 infection (COVID-19). However, their immune response to vaccination may vary among individuals.
Dali Wang, Fenghua Zhang
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Crosstalk Between ER Stress, Autophagy and Inflammation
Frontiers in Medicine, 2021 The endoplasmic reticulum (ER) is not only responsible for protein synthesis and folding but also plays a critical role in sensing cellular stress and maintaining cellular homeostasis.
Sandhya Chipurupalli +2 more
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STAR Protocols, 2022 Summary: Sr35, a coiled-coil nucleotide-binding leucine-rich repeat receptor (CC-NLR) from the wheat species Triticum monococcum can directly recognize the pathogen avirulence factor AvrSr35 and confers immunity against wheat stem rust caused by Puccinia
Meng-Xi Liu +4 more
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Cancer cells adapt FAM134B/BiP mediated ER-phagy to survive hypoxic stress
Cell Death and Disease, 2022 In the tumor microenvironment, cancer cells experience hypoxia resulting in the accumulation of misfolded/unfolded proteins largely in the endoplasmic reticulum (ER).
Sandhya Chipurupalli +10 more
doaj +1 more source
Cellular immune responses to HIV [PDF]
Nature, 2001 The cellular immune response to the human immunodeficiency virus, mediated by T lymphocytes, seems strong but fails to control the infection completely. In most virus infections, T cells either eliminate the virus or suppress it indefinitely as a harmless, persisting infection.
Mcmichael, A, Rowland-Jones, S
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Autophagy and Cellular Immune Responses [PDF]
Immunity, 2013 Autophagy constitutes a mechanism for the sequestration and lysosomal degradation of various cytoplasmic structures, including damaged organelles and invading microorganisms. Autophagy not only represents an essential cell-intrinsic mechanism to protect against internal and external stress conditions but also shapes cellular immunity.
Yuting Ma +3 more
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Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1
Nature Communications, 2021 Here, structures of the Cas12i1 R-loop complexes before and after target DNA cleavage and biochemical assays offer detailed insights into the mechanisms of target DNA duplex unwinding, R-loop formation and DNA cleavage, and suggest that Cas12i1 forms a ...
Bo Zhang +7 more
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Pharmacological STING Activation Is a Potential Alternative to Overcome Drug-Resistance in Melanoma
Frontiers in Oncology, 2020 Melanoma is the most aggressive type of skin cancer and resistance to the conventional chemotherapy is the major cause for its poor prognosis. Metabolic perturbations leading to increased production of reactive oxygen species activate NRF2-dependent anti-
Sandhya Chipurupalli +5 more
doaj +1 more source