Results 11 to 20 of about 1,059,847 (263)
Functional Features and Current Applications of the RNA‐Targeting Type VI CRISPR‐Cas Systems
Advanced Science, 2021 CRISPR‐Cas systems are a form of prokaryotic adaptive immunity that employs RNA‐guided endonucleases (Cas effectors) to cleave foreign genetic elements.
Vanja Perčulija +3 more
doaj +1 more source
Structural Basis for the Action Mechanism of Legionella Glycosyltransferase
Small Structures, 2023 Pathogenic bacterium Legionella pneumophila, the causative agent of Legionnaires’ disease, secretes hundreds of effectors into host cells that subvert cell pathways during pathogenesis.
Tao-Tao Chen +8 more
doaj +1 more source
Nature Communications, 2022 Here, the authors demonstrate that the Legionella pneumophila T4SS effector protein Lpg2370 is a Ser/Thr kinase and a toxin of a tripartite HipBST toxin-antitoxin (TA) system.
Xiangkai Zhen +10 more
doaj +1 more source
High expression level of MMP9 is associated with poor prognosis in patients with clear cell renal carcinoma [PDF]
PeerJ, 2018 Matrix metallopeptidase 9 (MMP9) was found to be associated with tumor aggressiveness. In this study, we focused on the correlation between MMP9 expression and clear cell renal carcinoma (ccRCC).
Haitao Niu +5 more
doaj +2 more sources
CD39 and control of cellular immune responses [PDF]
Purinergic Signalling, 2007 CD39 is the cell surface-located prototypic member of the ecto-nucleoside triphosphate diphosphohydrolase (E-NTPDase) family. Biological actions of CD39 are a consequence (at least in part) of the regulated phosphohydrolytic activity on extracellular nucleotides.
Dwyer, Karen M. +5 more
openaire +4 more sources
Immune disorders and COVID-19 vaccination: analysing anti-SARS-CoV-2 antibody levels and cellular immune response [PDF]
Central European Journal of ImmunologyJoanna Szczepanek +5 more
doaj +2 more sources
Evolutionarily conserved regulation of immunity by the splicing factor RNP-6/PUF60
eLife, 2020 Splicing is a vital cellular process that modulates important aspects of animal physiology, yet roles in regulating innate immunity are relatively unexplored. From genetic screens in C.
Chun Kew +5 more
doaj +1 more source
Cellular Immune Response to COVID-19 and Potential Immune Modulators
Frontiers in Immunology, 2021 Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Droplets and contacts serve as the main route of transmission of SARS-CoV-2. The characteristic of the disease
Xi Zhou, Qing Ye
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Microbiology Spectrum, 2023 Immunity following infection and vaccination with the SARS-CoV-2 Omicron variant is poorly understood. The aim was to investigate immunity assessed with antibody response, neutralizing antibodies (NAbs), and IFN-γ release under different scenarios: in ...
Maria Skaalum Petersen +10 more
doaj +1 more source
iScience, 2023 Summary: Metabolism and energy processes governing oligodendrocyte function during neuroinflammatory disease are of great interest. However, how varied cellular environments affect oligodendrocyte activity during neuroinflammation is unknown.
Hamid Suhail +13 more
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