Results 21 to 30 of about 1,059,847 (263)
Regulation of cGAS‐Mediated Immune Responses and Immunotherapy
Advanced Science, 2020 Early detection of infectious nucleic acids released from invading pathogens by the innate immune system is critical for immune defense. Detection of these nucleic acids by host immune sensors and regulation of DNA sensing pathways have been significant ...
Abdullah F. U. H. Saeed +4 more
doaj +1 more source
Molecular Basis of Ubiquitination Catalyzed by the Bacterial Transglutaminase MavC
Advanced Science, 2020 The Legionella pneumophila effector MavC is a transglutaminase that carries out atypical ubiquitination of the host ubiquitin (Ub)‐conjugation enzyme UBE2N by catalyzing the formation of an isopeptide bond between Gln40Ub and Lys92UBE2N, which leads to ...
Hongxin Guan +9 more
doaj +1 more source
Cellular immune response to HTLV-1 [PDF]
Oncogene, 2005 There is strong evidence at the individual level and the population level that an efficient cytotoxic T lymphocyte (CTL) response to HTLV-1 limits the proviral load and the risk of associated inflammatory diseases such as HAM/TSP. This evidence comes from host population genetics, viral genetics, DNA expression microarrays and assays of lymphocyte ...
Charles R M, Bangham, Mitsuhiro, Osame
openaire +2 more sources
Molecular Oncology, 2019 In malignant transformation, cellular stress‐response pathways are dynamically mobilized to counterbalance oncogenic activity, keeping cancer cells viable.
Matheus H. Dias +10 more
doaj +1 more source
Local cellular immune response in chronic periodontitis
Медицинская иммунология, 2021 Microflora of the oral cavity forms a biofilm that induces response of immune system at the mucous membranes. Transition to periodontal lesion is provided by certain classes of resident mucosal immune cells and inflammatory/immune cells migrating to the ...
V. P. Mudrov +3 more
doaj +1 more source
Cellular immunity in ASFV responses
Virus Research, 2013 African swine fever virus (ASFV) infection usually results in an acute haemorrhagic disease with a mortality rate approaching 100% in domestic pigs. However, pigs can survive infection with less-virulent isolates of ASFV and may become chronically infected.
Haru-Hisa, Takamatsu +8 more
openaire +2 more sources
Cellular immune response and pathology in schistosomiasis [PDF]
Parasite, 1996 In the present review, some aspects of the cellular response following the murine Schistosoma mansoni infection are described. Due to the peculiar route used by the schistosome to infect its definitive host, the skin appears as a critical site in which the initial events of the host/parasite relationship occur and where the immune response is initiated.
C, Auriault +5 more
openaire +2 more sources
Frontiers in Microbiology, 2021 Bacterial pathogens are a major cause of infectious diseases in aquatic animals. The abuse of antibiotics in the aquatic industry has led to the proliferation of antibiotic resistance.
Yuanyuan Gao +7 more
doaj +1 more source
Maternal Immunological Adaptation During Normal Pregnancy
Frontiers in Immunology, 2020 The risk and severity of specific infections are increased during pregnancy due to a combination of physiological and immunological changes. Characterizing the maternal immune system during pregnancy is important to understand how the maternal immune ...
Bahaa Abu-Raya +13 more
doaj +1 more source
HIV's evasion of the cellular immune response [PDF]
Immunological Reviews, 1999 Summary: Despite a strong cytotoxic T‐lymphocyte (CTL) response directed against viral antigens, untreated individuals infected with the human immunodeficiency virus (HIV‐1) develop AIDS, We have found that primary T cells infected with HIV‐1 downregulate surface MHC class I antigens and are resistant to lysis by HLA‐A2‐restricted CTL clones.
Collins, Kathleen L., Baltimore, David
openaire +3 more sources