Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy.
Yiping Yang +5 more
semanticscholar +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Influenza virus and Staphylococcus aureus super-infection disrupts spatially coordinated cellular immunity in the mouse lung. [PDF]
Liu T +9 more
europepmc +1 more source
FRI0326 Immune cellular profile associated with different treatment outcome in patients with systemic lupus erythematosus on cyclophosphamide [PDF]
Gabriela Gabčová +9 more
openalex +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Recombinant Bacillus subtilis spores expressing SARS-CoV-2 spike protein induced humoral, mucosal, and cellular immunity in mice. [PDF]
Hazan A +6 more
europepmc +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Longitudinal analysis of humoral and cellular immunity in SARS-CoV-2 exposed families. [PDF]
Dulovic A +25 more
europepmc +1 more source
818. Efficient Induction of Humoral and Cellular Immune Responses Against Her-2/neu by Combination of Naked DNA and Adenoviral Vectors Expressing Genetically Engineered Her-2/ neu [PDF]
openalex +1 more source

