Results 31 to 40 of about 3,445,878 (379)
Impaired Cellular Immunity to SARS-CoV-2 in Severe COVID-19 Patients
Frontiers in Immunology, 2020 The high infection rate and rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) make it a world-wide pandemic. Individuals infected by the virus exhibited different degrees of symptoms, and most convalescent individuals have been
L. Ni +18 more
semanticscholar +1 more source
Vaccines, 2023 Booster vaccination reduces the incidence of severe cases and mortality related to COVID-19, with cellular immunity playing an important role. However, little is known about the proportion of the population that has achieved cellular immunity after ...
Yuta Tani +18 more
doaj +1 more source
Structural insights into the biological functions of the long pentraxin PTX3
Frontiers in Immunology, 2023 Soluble pattern recognition molecules (PRMs) are a heterogenous group of proteins that recognize pathogen- and danger-associated molecular patterns (PAMPs and DAMPs, respectively), and cooperate with cell-borne receptors in the orchestration of innate ...
Anna Margherita Massimino +4 more
doaj +1 more source
A Conserved Tryptophan in the Envelope Cytoplasmic Tail Regulates HIV-1 Assembly and Spread
Viruses, 2022 The HIV-1 envelope (Env) is an essential determinant of viral infectivity, tropism and spread between T cells. Lentiviral Env contain an unusually long 150 amino acid cytoplasmic tail (EnvCT), but the function of the EnvCT and many conserved domains ...
Xenia Snetkov +5 more
doaj +1 more source
Journal of Clinical Immunology, 2022 We report the updated classification of inborn errors of immunity, compiled by the International Union of Immunological Societies Expert Committee. This report documents the key clinical and laboratory features of 55 novel monogenic gene defects, and 1 ...
S. Tangye +17 more
semanticscholar +1 more source
Heliyon, 2023 Background: The increasing evidence suggests that necroptosis mediates many behaviors of tumors, as well as the regulation of the tumor microenvironment.
Rongjie Zhang +12 more
doaj
Main Components of Fish Immunity: An Overview of the Fish Immune System
Fishes, 2023 Cellular immune responses consist of innate and adaptive cell-mediated immune mechanisms, where all leukocyte subpopulations are included. Among these are vital processes such as cell-mediated cytotoxicity and phagocytosis. The main cellular constituents
Doaa M. Mokhtar +5 more
semanticscholar +1 more source
In the absence of CD154, administration of interleukin-12 restores Th1 responses but not protective immunity to Schistosoma mansoni [PDF]
, 2007 The cytokine interplay during the development of protective immunity to the radiation-attenuated (RA) schistosome vaccine has been extensively characterized over recent years, yet the role of costimulatory molecules in the development of cell-mediated ...
Hamblin, Paul A +2 more
core +2 more sources
Autophagy and Cellular Immune Responses [PDF]
Immunity, 2013 Autophagy constitutes a mechanism for the sequestration and lysosomal degradation of various cytoplasmic structures, including damaged organelles and invading microorganisms. Autophagy not only represents an essential cell-intrinsic mechanism to protect against internal and external stress conditions but also shapes cellular immunity.
Yuting Ma +7 more
openaire +3 more sources
Unique Transcriptional Profile of Sustained Ligand-Activated Preconditioning in Pre- and Post-Ischemic Myocardium [PDF]
, 2013 BACKGROUND: Opioidergic SLP (sustained ligand-activated preconditioning) induced by 3–5 days of opioid receptor (OR) agonism induces persistent protection against ischemia-reperfusion (I-R) injury in young and aged hearts, and is mechanistically distinct
Ashton, Kevin J. +6 more
core +3 more sources