Results 31 to 40 of about 3,724,194 (363)

Impaired Cellular Immunity to SARS-CoV-2 in Severe COVID-19 Patients

Frontiers in Immunology, 2020
The high infection rate and rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) make it a world-wide pandemic. Individuals infected by the virus exhibited different degrees of symptoms, and most convalescent individuals have been
L. Ni, Mengli Cheng, Yu Feng, Hui Zhao, Jingyuan Liu, F. Ye, Qing Ye, Gengzheng Zhu, Xiaoli Li, Pengzhi Wang, Jing Shao, Yongqiang Deng, P. Wei, Fang Chen, C. Qin, Guoqing Wang, Fan Li, H. Zeng, C. Dong   +18 more
semanticscholar   +1 more source

Human Inborn Errors of Immunity: 2022 Update on the Classification from the International Union of Immunological Societies Expert Committee

Journal of Clinical Immunology, 2022
We report the updated classification of inborn errors of immunity, compiled by the International Union of Immunological Societies Expert Committee. This report documents the key clinical and laboratory features of 55 novel monogenic gene defects, and 1 ...
S. Tangye, W. Al-Herz, A. Bousfiha, C. Cunningham-Rundles, J. Franco, S. Holland, C. Klein, T. Morio, É. Oksenhendler, C. Picard, A. Puel, J. Puck, M. Seppänen, R. Somech, H. Su, K. Sullivan, T. Torgerson, I. Meyts   +17 more
semanticscholar   +1 more source

Main Components of Fish Immunity: An Overview of the Fish Immune System

Fishes, 2023
Cellular immune responses consist of innate and adaptive cell-mediated immune mechanisms, where all leukocyte subpopulations are included. Among these are vital processes such as cell-mediated cytotoxicity and phagocytosis. The main cellular constituents
Doaa M. Mokhtar, G. Zaccone, Alessio Alesci, M. Kuciel, Manal T. Hussein, Ramy K. A. Sayed   +5 more
semanticscholar   +1 more source

Vaccine-induced protection against SARS-CoV-2 requires IFN-γ-driven cellular immune response

Nature Communications, 2023
The overall success of worldwide mass vaccination in limiting the negative effect of the COVID-19 pandemics is inevitable, however, recent SARS-CoV-2 variants of concern, especially Omicron and its sub-lineages, efficiently evade humoral immunity mounted
Xiaolei Wang, Terrence Tsz-Tai Yuen, Ying Dou, Jingchu Hu, Renhao Li, Zheng Zeng, Xuansheng Lin, Huarui Gong, Celia Hoi-Ching Chan, Chaemin Yoon, Huiping Shuai, Deborah Tip-Yin Ho, Ivan Fan-Ngai Hung, Bao-Zhong Zhang, Hin Chu, Jian-Dong Huang   +15 more
doaj   +1 more source

Drosophila Cellular Immunity Against Parasitoid Wasps: A Complex and Time-Dependent Process

Frontiers in Physiology, 2019
Host-parasitoid interactions are among the most studied interactions between invertebrates because of their fundamental interest – the evolution of original traits in parasitoids – and applied, parasitoids being widely used in biological control ...
Chami Kim-Jo, J. Gatti, M. Poirié
semanticscholar   +1 more source

Reprogramming Exosomes as Nanoscale Controllers of Cellular Immunity.

Journal of the American Chemical Society, 2018
Exosomes are naturally occurring membranous vesicles secreted by various types of cells. Given their unique and important biological and pharmacological properties, exosomes have been emerging as a promising form of nanomedicine acting via efficient ...
Qinqin Cheng, Xiaojing Shi, Menglu Han, Goar Smbatyan, H. Lenz, Yong Zhang   +5 more
semanticscholar   +1 more source

Partial recovery of SARS-CoV-2 immunity after booster vaccination in renal transplant recipients

Clinical Immunology Communications, 2023
The pandemic caused by the SARS-CoV-2 coronavirus has been especially detrimental to patients with end-stage renal disease. History with other vaccines suggests that patients with renal disease may not respond adequately to the SARS-CoV-2 vaccine.
J.M. Urra, P. Castro, N. Jiménez, E. Moral, C. Vozmediano   +4 more
doaj   +1 more source

Restriction Factors: From Intrinsic Viral Restriction to Shaping Cellular Immunity Against HIV-1

Frontiers in Immunology, 2018
Antiviral restriction factors are host cellular proteins that constitute a first line of defense blocking viral replication and propagation. In addition to interfering at critical steps of the viral replication cycle, some restriction factors also act as
M. Colomer-Lluch, Alba Ruíz, A. Moris, J. Prado   +3 more
semanticscholar   +1 more source

Trial watch: anticancer vaccination with dendritic cells

OncoImmunology
Dendritic cells (DCs) are critical players at the intersection of innate and adaptive immunity, making them ideal candidates for anticancer vaccine development.
Francisca Borges, Raquel S. Laureano, Isaure Vanmeerbeek, Jenny Sprooten, Octavie Demeulenaere, Jannes Govaerts, Lisa Kinget, Saurabh Saraswat, Benoit Beuselinck, Steven De Vleeschouwer, Paul Clement, Frederik De Smet, Rüdiger V. Sorg, Angeliki Datsi, Nathalie Vigneron, Stefan Naulaerts, Abhishek D. Garg   +16 more
doaj   +1 more source

Langat virus infection affects hippocampal neuron morphology and function in mice without disease signs

Journal of Neuroinflammation, 2020
Background Tick-borne encephalitis virus (TBEV) is an important human pathogen that can cause the serious illness tick-borne encephalitis (TBE). Patients with clinical symptoms can suffer from severe meningoencephalitis with sequelae that include ...
Angela D. A. Cornelius, Shirin Hosseini, Sarah Schreier, David Fritzsch, Loreen Weichert, Kristin Michaelsen-Preusse, Markus Fendt, Andrea Kröger   +7 more
doaj   +1 more source