Stochastic Hybrid Systems in Cellular Neuroscience. [PDF]
We review recent work on the theory and applications of stochastic hybrid systems in cellular neuroscience. A stochastic hybrid system or piecewise deterministic Markov process involves the coupling between a piecewise deterministic differential equation and a time-homogeneous Markov chain on some discrete space.
Bressloff PC, Maclaurin JN.
europepmc +8 more sources
Bridging molecular and cellular neuroscience with proximity labeling technologies. [PDF]
Abstract Proximity labeling (PL) techniques have advanced neuroscience by revealing the molecular interactions that govern neural circuits. From foundational tools such as BioID and APEX to recent innovations such as TurboID and light-activated systems, PL enables precise mapping of protein–protein interactions within living cells.
Lee JG, Jeong I, Kim KE.
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Old innovations and shifted paradigms in cellular neuroscience. [PDF]
Once upon a time the statistics of quantal release were fashionable: “n” available vesicles (fusion sites), each with probability “p” of releasing a quantum. The story was not so simple, a nice paradigm to be abandoned. Biophysicists, experimenting with “black films,” explained the astonishing rapidity of spike-induced release: calcium can trigger the ...
Fesce R.
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Interpreting BOLD: towards a dialogue between cognitive and cellular neuroscience. [PDF]
Cognitive neuroscience depends on the use of blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) to probe brain function. Although commonly used as a surrogate measure of neuronal activity, BOLD signals actually reflect changes in brain blood oxygenation.
Hall CN +3 more
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Editorial: New challenges and future perspectives in cellular neuroscience. [PDF]
Arias N, Panuccio G, Rothermel M.
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Editorial: Paradigm shifts and innovations in cellular neuroscience. [PDF]
Cherubini E +5 more
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Cellular and chemical neuroscience of mammalian sleep [PDF]
Extraordinary strides have been made toward understanding the complexities and regulatory mechanisms of sleep over the past two decades thanks to the help of rapidly evolving technologies. At its most basic level, mammalian sleep is a restorative process of the brain and body.
Subimal Datta
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Large brains: Big unknowns in cellular neuroscience
Contemporary cellular neuroscience is strong on small but weak on large brains. Large brains have lower neuronal densities than smaller brains. We outline opposing functional interpretations of this result. Analysis of human brains supports the idea that dendritic complexity matters and might even correlate with intellectual ability.
Michael Brecht
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Peptide-enhanced cellular internalization of proteins in neuroscience
Over the last 15 years, many publications described the use of peptide sequences that have been dubbed cell penetrating peptides (CPP), Trojan Horse peptides, protein transduction domains, or membrane-translocating sequences. These mostly positively charged domains bring attached cargo across biological membranes. One of the reasons for the interest in
Gunnar P.H. Dietz, Mathias Bähr
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Editorial: 15 years of frontiers in cellular neuroscience: myelination and remyelination processes. [PDF]
Qiu Q, Hu B.
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