Results 1 to 10 of about 221,731 (288)

Stochastic Hybrid Systems in Cellular Neuroscience. [PDF]

open access: bronzeJ Math Neurosci, 2018
We review recent work on the theory and applications of stochastic hybrid systems in cellular neuroscience. A stochastic hybrid system or piecewise deterministic Markov process involves the coupling between a piecewise deterministic differential equation and a time-homogeneous Markov chain on some discrete space.
Bressloff PC, Maclaurin JN.
europepmc   +8 more sources

Bridging molecular and cellular neuroscience with proximity labeling technologies. [PDF]

open access: goldExp Mol Med
Abstract Proximity labeling (PL) techniques have advanced neuroscience by revealing the molecular interactions that govern neural circuits. From foundational tools such as BioID and APEX to recent innovations such as TurboID and light-activated systems, PL enables precise mapping of protein–protein interactions within living cells.
Lee JG, Jeong I, Kim KE.
europepmc   +5 more sources

Old innovations and shifted paradigms in cellular neuroscience. [PDF]

open access: goldFront Cell Neurosci
Once upon a time the statistics of quantal release were fashionable: “n” available vesicles (fusion sites), each with probability “p” of releasing a quantum. The story was not so simple, a nice paradigm to be abandoned. Biophysicists, experimenting with “black films,” explained the astonishing rapidity of spike-induced release: calcium can trigger the ...
Fesce R.
europepmc   +6 more sources

Interpreting BOLD: towards a dialogue between cognitive and cellular neuroscience. [PDF]

open access: bronzePhilos Trans R Soc Lond B Biol Sci, 2016
Cognitive neuroscience depends on the use of blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) to probe brain function. Although commonly used as a surrogate measure of neuronal activity, BOLD signals actually reflect changes in brain blood oxygenation.
Hall CN   +3 more
europepmc   +6 more sources

Editorial: Paradigm shifts and innovations in cellular neuroscience. [PDF]

open access: goldFront Cell Neurosci
Cherubini E   +5 more
europepmc   +5 more sources

Cellular and chemical neuroscience of mammalian sleep [PDF]

open access: greenSleep Medicine, 2010
Extraordinary strides have been made toward understanding the complexities and regulatory mechanisms of sleep over the past two decades thanks to the help of rapidly evolving technologies. At its most basic level, mammalian sleep is a restorative process of the brain and body.
Subimal Datta
openalex   +4 more sources

Large brains: Big unknowns in cellular neuroscience

open access: hybridCurrent Opinion in Neurobiology
Contemporary cellular neuroscience is strong on small but weak on large brains. Large brains have lower neuronal densities than smaller brains. We outline opposing functional interpretations of this result. Analysis of human brains supports the idea that dendritic complexity matters and might even correlate with intellectual ability.
Michael Brecht
openalex   +3 more sources

Peptide-enhanced cellular internalization of proteins in neuroscience

open access: goldBrain Research Bulletin, 2005
Over the last 15 years, many publications described the use of peptide sequences that have been dubbed cell penetrating peptides (CPP), Trojan Horse peptides, protein transduction domains, or membrane-translocating sequences. These mostly positively charged domains bring attached cargo across biological membranes. One of the reasons for the interest in
Gunnar P.H. Dietz, Mathias Bähr
openalex   +4 more sources

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