Results 241 to 250 of about 224,348 (348)

Cancer Cell‐Intrinsic Cholesterol Induces Lipid‐Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression

open access: yesAdvanced Science, EarlyView.
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng   +12 more
wiley   +1 more source

CellPolaris: Transfer Learning for Gene Regulatory Network Construction to Guide Cell State Transitions

open access: yesAdvanced Science, EarlyView.
CellPolaris decodes how transcription factors guide cell fate by building gene regulatory networks from transcriptomic data using transfer learning. It generates tissue‐ and cell‐type‐specific networks, identifies master regulators in cell state transitions, and simulates TF perturbations in developmental processes.
Guihai Feng   +27 more
wiley   +1 more source

An Unbiased Approach to Identifying Cellular Reprogramming-Inducible Enhancers. [PDF]

open access: yesInt J Mol Sci
Klagkou E   +6 more
europepmc   +1 more source

Cellular Reprogramming and Its Potential Application in Alzheimer's Disease. [PDF]

open access: yesFront Neurosci, 2022
Zhou C   +5 more
europepmc   +1 more source

A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan   +11 more
wiley   +1 more source

Correction: Engineering extracellular vesicles for ROS scavenging and tissue regeneration

open access: yesNano Convergence
Ahmed Abdal Dayem   +6 more
doaj   +1 more source

Biological models and genes of tumor reversion: Cellular reprogramming through tpt1 /TCTP and SIAH-1

open access: green, 2002
Marcel Tuynder   +6 more
openalex   +1 more source

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