Results 51 to 60 of about 233,840 (301)

Epigenetic Control of Reprogramming and Cellular Differentiation [PDF]

open access: yesComparative and Functional Genomics, 2012
Recently, numerous interdisciplinary approaches that include integration of bioinformatics, epigenetics, and molecular and cellular biology have started to shed light on the complex dynamics that regulate cellular processes such as cell “stemness,” reprogramming, and differentiation.
Latella L.   +3 more
openaire   +3 more sources

Comparison of Developmental Efficiency of Murine Somatic Cell Nuclear Transfer Protocol

open access: yesJournal of Animal Reproduction and Biotechnology, 2017
The Somatic cell nuclear transfer (SCNT) method can be applied to various fields such as species conservation, regenerative medicine, farming industries and drug production. However, the efficiency using SCNT is very low for many reasons.
Jeonghyeon Moon, Miran Jung, Sangho Roh
doaj   +1 more source

Biomarker Candidates for Alzheimer’s Disease Unraveled through In Silico Differential Gene Expression Analysis

open access: yesDiagnostics, 2022
Alzheimer’s disease (AD) is neurodegeneration that accounts for 60–70% of dementia cases. Symptoms begin with mild memory difficulties and evolve towards cognitive impairment.
Maria-del-Carmen Silva-Lucero   +8 more
doaj   +1 more source

Generation of induced pluripotent stem cells (iPSC) from an atrial fibrillation patient carrying a KCNA5 p.D322H mutation

open access: yesStem Cell Research, 2017
Atrial fibrillation (AF) is the most common sustained arrhythmia associated with several cardiac risk factors, but increasing evidences indicated a genetic component.
Cristina Mora   +11 more
doaj   +1 more source

New Insights into X-Chromosome Reactivation during Reprogramming to Pluripotency

open access: yesCells, 2020
Dosage compensation between the sexes results in one X chromosome being inactivated during female mammalian development. Chromosome-wide transcriptional silencing from the inactive X chromosome (Xi) in mammalian cells is erased in a process termed X ...
Amitesh Panda   +2 more
doaj   +1 more source

New directions in cellular therapy of cancer: a summary of the summit on cellular therapy for cancer [PDF]

open access: yes, 2012
A summit on cellular therapy for cancer discussed and presented advances related to the use of adoptive cellular therapy for melanoma and other cancers. The summit revealed that this field is advancing rapidly.
A Lundqvist   +48 more
core   +4 more sources

Chromatin Connections to Pluripotency and Cellular Reprogramming [PDF]

open access: yesCell, 2011
The pluripotent state of embryonic stem cells (ESCs) provides a unique perspective on regulatory programs that govern self-renewal and differentiation and somatic cell reprogramming. Here, we review the highly connected protein and transcriptional networks that maintain pluripotency and how they are intertwined with factors that affect chromatin ...
Orkin, Stuart H., Hochedlinger, Konrad
openaire   +2 more sources

Dynamical systems theory of cellular reprogramming

open access: yesPhysical Review Research, 2022
15 pages, 12 ...
Yuuki Matsushita   +2 more
openaire   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Re: Epigenetics of Cellular Reprogramming

open access: yesJournal of Urological Surgery, 2016
EDITORIAL COMMENT Cells have some specific molecular and physiological properties that act their functional process. However, many cells have an ability of efficient transition from one type to another. This ability is named plasticity.
Fehmi Narter
doaj   +1 more source

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