Results 251 to 260 of about 234,206 (306)

Exploration of genes associated with cellular senescence in lung ischemia-reperfusion injury and connection to immune infiltration. [PDF]

Clin Exp Med
Wang M, Liu L, Liu Y, Zhao Y, Yu S.
europepmc   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Identification and validation of biomarkers associated with cellular senescence and demethylation in acute myocardial infarction. [PDF]

Sci Rep
Su W, Huang H, Ruan Q, Liu S, Dan J, Zhao Y, Zhang H, Huo Q.   +7 more
europepmc   +1 more source

Mitochondrial dysfunction in cellular senescence

L. Solomko, Assiya Kussainova, Olga Bulgakova   +2 more
openalex   +2 more sources

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Targeting Cellular Senescence for Healthy Aging: Advances in Senolytics and Senomorphics. [PDF]

Drug Des Devel Ther
Alum EU, Izah SC, Uti DE, Ugwu OP, Betiang PA, Basajja M, Ejemot-Nwadiaro RI.   +6 more
europepmc   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Heterogeneity of Cellular Senescence: Subtype-Specific Mechanisms and the Emerging Role of Plasma Membrane Damage. [PDF]

Cancer Sci
Alghamdi E, Kono K.
europepmc   +1 more source

Cyclosporine A ameliorates ulcerative colitis by inhibiting cellular senescence, modulating the JAK2-STAT3/NF-κB signaling pathway, and regulating the gut microbiota-metabolite axis

Bingxiang Zhao, Yingjie Xu, Fuxing Li, Shujia Song, Zhenlin Liu, Jiayu Liu, Zhengze Liu, X. Peter Chen, xiao bo Wang, Hui Zhou, Linlin Zhao   +10 more
openalex   +1 more source

Collaboration networks and knowledge structure in cancer and cellular senescence research (2000-2025): a bibliometric perspective. [PDF]

Discov Oncol
Zhu H, Pan S, Zhou Y, Yi B, Jing Y, Ruan L, Huang L, Zhu X.   +7 more
europepmc   +1 more source