Results 231 to 240 of about 357,990 (305)

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Cellular senescence and cell therapy in cardiovascular diseases. [PDF]

Stem Cell Res Ther
Chang D, Wang J, Zhu S, Shentu Y, Wang Y, Zhu P, Ono M.   +6 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Cellular senescence in human liver under normal aging and cancer. [PDF]

Cell Genom
Karpova A, Li X, Peng CW, Gallant KL, Rapp DR, Alligood DM, Houston AJ, Park A, Targino da Costa ALN, Chou WH, Iglesia MD, Herndon JM, Byrnes K, Naser Al Deen N, Lal P, Fang X, Jayasinghe RG, Blatnik JA, Hawkins WG, Sanford DE, Eagon JC, Leigh N, Doyle MBM, Brunt LM, Chapman WC, Panni RZ, Cullinan DR, Davies SR, Guo J, Wyczalkowski MA, Wendl MC, Zhang H, Martin CA, Warner BW, Chheda MG, Stewart SA, Chen F, Fields RC, Ding L.   +38 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Cellular senescence and metabolic aging in type 2 diabetes: mechanistic insights and translational implications. [PDF]

Front Endocrinol (Lausanne)
Syed AR, Aloti RA, Awad BJ, Alghoul WII, Hassan MAMSA, Kharoufeh A, Rangraze I.   +6 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Cellular senescence in lung cancer immune microenvironment and senotherapeutic opportunities. [PDF]

iScience
Xu Z, Liu F, Huang S, Chu Q.
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Neuropilin-2 Deficiency Promotes Mitochondrial Dysfunction and NAD⁺-Dependent Cellular Senescence in Retinal Degeneration. [PDF]

Invest Ophthalmol Vis Sci
Ou L, Cui B, Zhou L, Liu K, Shi L, Zhou T, Zeng L, Zhou H, Xu H, Zheng Y, Zhou X, Li X, He C, Yi W, Zhang F, Ju R, Liu X.   +16 more
europepmc   +1 more source