Results 21 to 30 of about 1,723 (195)
Biotechnology for Biofuels, 2017 Background Bioethanol production processes involve enzymatic hydrolysis of pretreated lignocellulosic biomass into fermentable sugars. Due to the relatively high cost of enzyme production, the development of potent and cost-effective cellulolytic ...
Shahar Yoav +8 more
doaj +1 more source
Current challenges in designer cellulosome engineering
Applied Microbiology and Biotechnology, 2023 Designer cellulosomes (DCs) are engineered multi-enzyme complexes, comprising carbohydrate-active enzymes attached to a common backbone, the scaffoldin, via high-affinity cohesin-dockerin interactions. The use of DCs in the degradation of renewable biomass polymers is a promising approach for biorefineries. Indeed, DCs have shown significant hydrolytic
Babette Lamote +5 more
openaire +3 more sources
Nanoscale Engineering of Designer Cellulosomes
Advanced Materials, 2016 Biocatalysts showcase the upper limit obtainable for high‐speed molecular processing and transformation. Efforts to engineer functionality in synthetic nanostructured materials are guided by the increasing knowledge of evolving architectures, which enable controlled molecular motion and precise molecular recognition.
Gunnoo M. +12 more
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Deconstruction of Lignocellulose into Soluble Sugars by Native and Designer Cellulosomes
mBio, 2012 Lignocellulosic biomass, the most abundant polymer on Earth, is typically composed of three major constituents: cellulose, hemicellulose, and lignin. The crystallinity of cellulose, hydrophobicity of lignin, and encapsulation of cellulose by the lignin ...
Sarah Moraïs +8 more
doaj +1 more source
Recombinant Cellulase and Cellulosome Systems [PDF]
, 2013 The non-renewable fossil resources currently exploited by the oil and gas industries are the objects of growing concern owing to their finite supply and contribution to global warming. Lignocellulosic biomass is a sustainable alternative to fossil resources, and has the added advantage of not competing with human and animal nutrition.
Andrew Chi +2 more
openalex +4 more sources
Ruminococcus flavefaciens 007C cellulosomes and cellulase consortium
Acta Agriculturae Slovenica, 2014 Ruminococcus flavefaciens is among the most important cellulolytic bacterial species in rumen and gastrointestinal tract of monogastric herbivorous animals. Its efficiency in degradation of (hemi)cellulosic substrates is associated with the production of
Maša VODOVNIK
doaj +1 more source
Mapping the deformability of natural and designed cellulosomes in solution
Biotechnology for Biofuels and Bioproducts, 2022 Background Natural cellulosome multi-enzyme complexes, their components, and engineered ‘designer cellulosomes’ (DCs) promise an efficient means of breaking down cellulosic substrates into valuable biofuel products.
Jonathan Dorival +11 more
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Pan-Cellulosomics of Mesophilic Clostridia: Variations on a Theme
Microorganisms, 2017 The bacterial cellulosome is an extracellular, multi-enzyme machinery, which efficiently depolymerizes plant biomass by degrading plant cell wall polysaccharides.
Bareket Dassa +6 more
doaj +1 more source
Elaborate cellulosome architecture of Acetivibrio cellulolyticus revealed by selective screening of cohesin–dockerin interactions [PDF]
PeerJ, 2014 Cellulosic waste represents a significant and underutilized carbon source for the biofuel industry. Owing to the recalcitrance of crystalline cellulose to enzymatic degradation, it is necessary to design economical methods of liberating the fermentable ...
Yuval Hamberg +8 more
doaj +2 more sources
Adaptor Scaffoldins: An Original Strategy for Extended Designer Cellulosomes, Inspired from Nature
mBio, 2016 Designer cellulosomes consist of chimeric cohesin-bearing scaffoldins for the controlled incorporation of recombinant dockerin-containing enzymes. The largest designer cellulosome reported to date is a chimeric scaffoldin that contains 6 cohesins.
Johanna Stern +3 more
doaj +1 more source