Results 1 to 10 of about 4,511 (184)

Ethanol tolerance in engineered strains of Clostridium thermocellum [PDF]

Biotechnology for Biofuels and Bioproducts, 2023
Clostridium thermocellum is a natively cellulolytic bacterium that is promising candidate for cellulosic biofuel production, and can produce ethanol at high yields (75–80% of theoretical) but the ethanol titers produced thus far are too low for ...
Daniel G. Olson, Marybeth I. Maloney, Anthony A. Lanahan, Nicholas D. Cervenka, Ying Xia, Angel Pech-Canul, Shuen Hon, Liang Tian, Samantha J. Ziegler, Yannick J. Bomble, Lee R. Lynd   +10 more
doaj   +4 more sources

Expression of adhA from different organisms in Clostridium thermocellum [PDF]

Biotechnology for Biofuels, 2017
Background Clostridium thermocellum is a cellulolytic anaerobic thermophile that is a promising candidate for consolidated bioprocessing of lignocellulosic biomass into biofuels such as ethanol.
Tianyong Zheng, Jingxuan Cui, Hye Ri Bae, Lee R. Lynd, Daniel G. Olson   +4 more
doaj   +3 more sources

Metabolome Analysis of Constituents in Membrane Vesicles for Clostridium thermocellum Growth Stimulation [PDF]

Microorganisms, 2021
The cultivation of the cellulolytic bacterium, Clostridium thermocellum, can have cost-effective cellulosic biomass utilizations, such as consolidated bioprocessing, simultaneous biological enzyme production and saccharification. However, these processes
Shunsuke Ichikawa, Yoichiro Tsuge, Shuichi Karita   +2 more
doaj   +3 more sources

Deciphering Cellodextrin and Glucose Uptake in Clostridium thermocellum [PDF]

mBio, 2022
Sugar uptake is of great significance in industrially relevant microorganisms. Clostridium thermocellum has extensive potential in lignocellulose biorefineries as an environmentally prominent, thermophilic, cellulolytic bacterium.
Fei Yan, Sheng Dong, Ya-Jun Liu, Xingzhe Yao, Chao Chen, Yan Xiao, Edward A. Bayer, Yuval Shoham, Chun You, Qiu Cui, Yingang Feng   +10 more
doaj   +4 more sources

Genetic and metabolic drivers of membrane remodeling in Clostridium thermocellum under alcohol stress [PDF]

mSystems
Clostridium thermocellum is a leading candidate for consolidated bioprocessing of lignocellulosic biomass into biofuels due to its native cellulolytic capabilities. Beyond ethanol, C.
Eashant Thusoo, Tyler Jacobson, Bishal D. Sharma, Isabella M. Colón, Lee R. Lynd, Daniel G. Olson, Daniel Amador-Noguez   +6 more
doaj   +2 more sources

Engineering Clostridium thermocellum for production of 2,3-butanediol from cellulose [PDF]

Metabolic Engineering Communications
Clostridium thermocellum is a promising host for consolidated bioprocessing due to its ability to directly ferment cellulose into fuels and chemicals. However, natural product formation in this organism is limited.
S. Bilal Jilani, Nandhini Ashok, Yannick J. Bomble, Adam M. Guss, Daniel G. Olson   +4 more
doaj   +2 more sources

Structural characterization and dynamics of AdhE ultrastructures from Clostridium thermocellum show a containment strategy for toxic intermediates [PDF]

eLife
Clostridium thermocellum, a cellulolytic thermophilic anaerobe, is considered by many to be a prime candidate for the realization of consolidated bioprocessing (CBP) and is known as an industry standard for biofuel production. C.
Samantha J Ziegler, Brandon C Knott, Josephine N Gruber, Neal N Hengge, Qi Xu, Daniel G Olson, Eduardo E Romero, Lydia-Marie Joubert, Yannick J Bomble   +8 more
doaj   +2 more sources

Rhamnogalacturonan I is a recalcitrant pectin domain during Clostridium thermocellum-mediated deconstruction of switchgrass biomass [PDF]

Biotechnology for Biofuels and Bioproducts
Background Liquid fuels from lignocellulosic feedstocks are required for transition to a sustainable bioeconomy. However, the recalcitrance of carbon-containing feedstock cell walls to deconstruction poses a barrier to cost effective biological ...
Ajaya K. Biswal, Neal N. Hengge, Melani A. Atmodjo, Paul E. Abraham, Nancy L. Engle, Sushree S. Mohanty, Ian M. Black, Xiaochun Cheng, David Ryno, Parastoo Azadi, Timothy J. Tschaplinski, Yannick J. Bomble, Debra Mohnen   +12 more
doaj   +2 more sources

Expression and characterization of monofunctional alcohol dehydrogenase enzymes in Clostridium thermocellum [PDF]

Metabolic Engineering Communications
Clostridium thermocellum is a thermophilic anaerobic bacterium that could be used for cellulosic biofuel production due to its strong native ability to consume cellulose, however its ethanol production ability needs to be improved to enable commercial ...
Daniela Prates Chiarelli, Bishal Dev Sharma, Shuen Hon, Luana Walravens Bergamo, Lee R. Lynd, Daniel G. Olson   +5 more
doaj   +2 more sources

Genome-Wide Transcription Factor DNA Binding Sites and Gene Regulatory Networks in Clostridium thermocellum [PDF]

Frontiers in Microbiology, 2021
Clostridium thermocellum is a thermophilic bacterium recognized for its natural ability to effectively deconstruct cellulosic biomass. While there is a large body of studies on the genetic engineering of this bacterium and its physiology to-date, there ...
Skyler D. Hebdon, Alida T. Gerritsen, Yi-Pei Chen, Joan G. Marcano, Katherine J. Chou   +4 more
doaj   +2 more sources