Draft genome sequence data of Clostridium thermocellum PAL5 possessing high cellulose-degradation ability [PDF]
Data in Brief, 2019 Clostridium thermocellum is a potent cellulolytic bacterium. C. thermocellum strain PAL5, was derived from strain S14 that was isolated from bagasse paper sludge, possesses higher cellulose-degradation ability than representative strains ATCC27405 and ...
Eiko Nakazono-Nagaoka +7 more
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Expression of adhA from different organisms in Clostridium thermocellum [PDF]
Biotechnology for Biofuels, 2017 Background Clostridium thermocellum is a cellulolytic anaerobic thermophile that is a promising candidate for consolidated bioprocessing of lignocellulosic biomass into biofuels such as ethanol.
Tianyong Zheng +4 more
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Effects of heterologous expression of glycolysis enzymes on product formation in Clostridium thermocellumNCBI [PDF]
Metabolic Engineering CommunicationsGlycolysis is central to Clostridium thermocellum metabolism; however, strains engineered for high ethanol titer exhibit a decrease in the conversion of cellobiose to ethanol (i.e., cellobiose-to-ethanol yield), suggesting the presence of glycolytic ...
Daniela Prates Chiarelli +3 more
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Coculture with hemicellulose-fermenting microbes reverses inhibition of corn fiber solubilization by Clostridium thermocellum at elevated solids loadings [PDF]
Biotechnology for Biofuels, 2021 Background The cellulolytic thermophile Clostridium thermocellum is an important biocatalyst due to its ability to solubilize lignocellulosic feedstocks without the need for pretreatment or exogenous enzyme addition. At low concentrations of substrate, C.
Dhananjay Beri +6 more
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Development of a Genome-Scale Metabolic Model of Clostridium thermocellum and Its Applications for Integration of Multi-Omics Datasets and Computational Strain Design [PDF]
Frontiers in Bioengineering and Biotechnology, 2020 Solving environmental and social challenges such as climate change requires a shift from our current non-renewable manufacturing model to a sustainable bioeconomy.
Sergio Garcia +14 more
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Metabolic adaption of ethanol-tolerant Clostridium thermocellum.
PLoS ONE, 2013 Clostridium thermocellum is a major candidate for bioethanol production via consolidated bioprocessing. However, the low ethanol tolerance of the organism dramatically impedes its usage in industry.
Xinshu Zhu +5 more
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Simultaneous expression of an endogenous spermidine synthase and a butanol dehydrogenase from Thermoanaerobacter pseudethanolicus in Clostridium thermocellum results in increased resistance to acetic acid and furans, increased ethanol production and an increase in thermotolerance [PDF]
Biotechnology for Biofuels and Bioproducts, 2023 Background Sensitivity to inhibitors derived from the pretreatment of plant biomass is a barrier to the consolidated bioprocessing of these complex substrates to fuels and chemicals by microbes.
Sun-Ki Kim +2 more
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Metabolic engineering of Clostridium thermocellum for n-butanol production from cellulose [PDF]
Biotechnology for Biofuels, 2019 Background Biofuel production from plant cell walls offers the potential for sustainable and economically attractive alternatives to petroleum-based products. In particular, Clostridium thermocellum is a promising host for consolidated bioprocessing (CBP)
Liang Tian +6 more
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mSystems, 2020 Clostridium thermocellum and Thermoanaerobacterium saccharolyticum are thermophilic anaerobic bacteria with complementary metabolic capabilities that utilize distinct glycolytic pathways for the conversion of cellulosic sugars to biofuels.
Tyler B. Jacobson +7 more
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Pyrophosphate-free glycolysis in Clostridium thermocellum increases both thermodynamic driving force and ethanol titers [PDF]
Biotechnology for Biofuels and BioproductsBackground Clostridium thermocellum is a promising candidate for production of cellulosic biofuels, however, its final product titer is too low for commercial application, and this may be due to thermodynamic limitations in glycolysis.
Bishal Dev Sharma +7 more
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