New Antiproliferative Cembrane Diterpenes from the Red Sea Sarcophyton Species [PDF]
Marine Drugs, 2019 The combination of liquid chromatography coupled to high resolution mass spectrometry (LC-HRESMS)-based dereplication and antiproliferative activity-guided fractionation was applied on the Red Sea-derived soft coral Sarcophyton sp.
Hossam M. Hassan +11 more
doaj +3 more sources
Bioactive Capnosanes and Cembranes from the Soft Coral Klyxum flaccidum [PDF]
Marine Drugs, 2019 Two new capnosane-based diterpenoids, flaccidenol A (1) and 7-epi-pavidolide D (2), two new cembranoids, flaccidodioxide (3) and flaccidodiol (4), and three known compounds 5 to 7 were characterized from the marine soft coral Klyxum flaccidum, collected ...
Wan-Ru Tseng +9 more
doaj +5 more sources
Anti-Protozoal Activities of Cembrane-Type Diterpenes from Vietnamese Soft Corals [PDF]
Molecules, 2015 Based on our previous finding that certain cembranoid diterpenes possess selective toxicity against protozoan pathogens of tropical diseases such as Trypanosoma and Plasmodium, we have subjected a series of 34 cembranes isolated from soft corals living ...
Nguyen Phuong Thao +8 more
doaj +7 more sources
Discovery of papyifuran A as an unusual cembrane diterpenoid from <i>Boswellia papyrifera</i> resin reveals EEF2 as a potent new drug target for fibrosis of multiple organs. [PDF]
Acta Pharm Sin BSura MB, Zhou Y, Li J, Cheng Y.
europepmc +3 more sources
Anti-Inflammatory Cembrane-Type Diterpenoids and Prostaglandins from Soft Coral Lobophytum sarcophytoides [PDF]
Marine Drugs, 2019 Two new cembrane-type diterpenoids, lobophytins A (1) and B (3), and four new prostaglandins, (5E)-PGB2 (10), (5E)-13,14-dihydro-PGB2 (11), 13,14-dihydro-PGB2 (12) and 13,14-dihydro-PGB2-Me (13), together with ten known compounds were isolated from the ...
Hongjie Shen +8 more
doaj +3 more sources
A New Cembrane Diterpene from the Bornean Soft Coral Nephthea sp. [PDF]
Molecules, 2010 A new cembrane diterpene, 6-acetoxy-7,8-epoxynephthenol acetate (1) was isolated along with a known compound, epoxynephthenol acetate (2), from the organic extract of a Bornean soft coral Nephthea sp.
Takahiro Ishii +2 more
doaj +5 more sources
Bioactive Cembrane-Based Diterpenoids from the Soft Coral Sinularia triangular [PDF]
Marine Drugs, 2011 Chemical examination of the Taiwanese soft coral Sinularia triangular led to the isolation of five cembrane-based diterpenoids 1–5, including two new metabolites, triangulenes A (1) and B (2).
Jui-Hsin Su, Zhi-Hong Wen
doaj +6 more sources
Cembrane-type diterpenoids from the South China Sea soft coral Sarcophyton mililatensis
Acta Pharmaceutica Sinica B, 2018 Eight cembrane-type diterpenoids, namely, (+)-(6R)-6-hydroxyisosarcophytoxide (1), (+)-(6R)-6-acetoxyisosarcophytoxide (2), (+)-17-hydroxyisosarcophytoxide (3), sarcomililatins A–D (4–7), and sarcomililatol (8), were isolated from the soft coral ...
Songwei Li +5 more
doaj +3 more sources
Cembrane Derivatives from the Soft Corals, Sinularia gaweli and Sinularia flexibilis [PDF]
Marine Drugs, 2013 A new norcembranoidal diterpene, 1-epi-sinulanorcembranolide A (1), and a new cembranoidal diterpene, flexibilin D (2), were isolated from the soft corals, Sinularia gaweli and Sinularia flexibilis, respectively. The structures of new metabolites 1 and 2
Yang-Chang Wu +11 more
doaj +6 more sources
Bioactive Cembrane Derivatives from the Indian Ocean Soft Coral, Sinularia kavarattiensis [PDF]
Marine Drugs, 2014 Marine organisms and their metabolites represent a unique source of potential pharmaceutical substances. In this study, we examined marine-derived substances for their bioactive properties in a cell-based Chikungunya virus (CHIKV) replicon model and for
Katja-Emilia Lillsunde +10 more
doaj +8 more sources