Results 21 to 30 of about 873 (161)

Activities and Molecular Mechanisms of Diterpenes, Diterpenoids, and Their Derivatives in Rheumatoid Arthritis

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Diterpenes and their derivatives have many biological activities, including anti‐inflammatory and immunomodulatory effects. To date, several diterpenes, diterpenoids, and their laboratory‐derived products have been demonstrated for antiarthritic activities.
Muhammad Torequl Islam, Cristina Quispe, Jesús Herrera-Bravo, Md. Mizanur Rahaman, Rajib Hossain, Chandan Sarkar, Md Abdur Raihan, Md. Mashrur Chowdhury, Shaikh Jamal Uddin, Jamil A. Shilpi, João Marcelo de Castro e Sousa, Ana Amélia de Carvalho Melo-Cavalcante, Mohammad S. Mubarak, Javad Sharifi-Rad, Daniela Calina, Yanhong Zhu   +15 more
wiley   +1 more source

Taxonomical Investigation, Chemical Composition, Traditional Use in Medicine, and Pharmacological Activities of Boswellia sacra Flueck

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Aromatic oleo‐gum‐resin secreted from B. sacra, reputed as frankincense, is widely used in traditional medicine to treat Alzheimer’s disease, gastric disorders, hepatic disorders, etc. Frankincense is also used in the cosmetic, perfume, and beverage and food industries. Frankincense is a rich resource for bioactive compounds, especially boswellic acids
Mansour Miran, Keyvan Amirshahrokhi, Yousef Ajanii, Reza Zadali, Maxwell W. Rutter, Ayesheh Enayati, Farahnaz Movahedzadeh, Mohammed Bourhia   +7 more
wiley   +1 more source

Anti-Inflammatory Cembranoids from the Soft Coral Lobophytum crassum

Marine Drugs, 2017
: Cembrane-type diterpenoids are among the most frequently encountered natural products from the soft corals of the genus Lobophytum. In the course of our investigation to identify anti-inflammatory constituents from a wild-type soft coral Lobophytum ...
Kuei-Hung Lai, Wan-Jing You, Chi-Chen Lin, Mohamed El-Shazly, Zuo-Jian Liao, Jui-Hsin Su   +5 more
doaj   +1 more source

Bioactive Cembranoids from the Soft Coral Genus Sinularia sp. in Borneo

Marine Drugs, 2018
Soft corals are known to be prolific producers of a wide spectrum of biologically active cembranoids. One new cembranoid, sinularolide F (2), along with three known compounds, cembranolide (1), (E,E,E)-6,10,14-trimethyl-3-methylene-cis-3α,4,5,8,9,12,13 ...
Takashi Kamada, Min-Cheol Kang, Chin-Soon Phan, Intan Irna Zanil, You-Jin Jeon, Charles S. Vairappan   +5 more
doaj   +1 more source

New Cembranoid Diterpenes from the Cultured Octocoral Nephthea columnaris

Molecules, 2015
Two new 15-hydroxycembranoid diterpenes, 2β-hydroxy-7β,8α-epoxynephthenol (1) and 2β-hydroxy-11α,12β-epoxynephthenol (2), were isolated from extracts of the octocoral Nephthea columnaris along with a new natural cembrane, epoxynephthenol (3) and a known ...
Ting-Hsi Hsiao, Ching-Hsiao Cheng, Tung-Ying Wu, Mei-Chin Lu, Wu-Fu Chen, Zhi-Hong Wen, Chang-Feng Dai, Yang-Chang Wu, Ping-Jyun Sung   +8 more
doaj   +1 more source

New Cembranoids from the Soft Coral

Natural Product Communications, 2014
From the ethyl acetate extract of the soft coral Sinularia arborea , a new cembrane-type diterpenoid, arbolide C ( 1 ), along with (+)-sarcophytol T ( 2 ), an enantiomer of the known cembrane, sarcophytol T, were isolated.
Li-Hsueh Wang, Kuan-Hua Chen, Chang-Feng Dai, Tsong-Long Hwang, Wei-Hsien Wang, Zhi-Hong Wen, Yang-Chang Wu, Ping-Jyun Sung   +7 more
doaj   +1 more source

A Great Barrier Reef <em>Sinularia</em> sp. Yields Two New Cytotoxic Diterpenes

Marine Drugs, 2012
The methanol extract of a <em>Sinularia </em>sp., collected from Bowden Reef, Queensland, Australia, yielded ten natural products. These included the new nitrogenous diterpene (4<em>R</em>*,5<em>R</em>*,9<em>S<
Cherie A. Motti, Catherine H. Liptrot, Anthony D. Wright, Jonathan L. Nielson, Dianne M. Tapiolas   +4 more
doaj   +1 more source

Cytotoxic Cembranes from Indonesian Specimens of the Soft Coral Nephthea sp.

Marine Drugs, 2010
Methanol extracts of two specimens of the soft coral Nephthea sp. collected from the Seribu Islands, Indonesia, were active in an anticancer bioassay. One new (1) and four known diterpenes (2–5) based on the cembrane carbon skeleton were isolated from ...
Dianne M. Tapiolas, Catherine H. Liptrot, Anthony D. Wright, Cherie A. Motti, Hedi Indra Januar, Ekowati Chasanah   +5 more
doaj   +1 more source

On the Role of Hydrogen Migrations in the Taxadiene System. [PDF]

Angew Chem Int Ed Engl
Long range proton migrations are known to play a role in the biosynthesis of taxa‐4,11‐diene. This study demonstrates the involvement of long distance hydrogen transfers also in the mass spectrometric fragmentation, and combined approaches through site‐directed mutagenesis and enzymatic conversion of designed substrate analogs give detailed insights ...
Li H, Goldfuss B, Dickschat JS.
europepmc   +2 more sources

Terpenoids from Octocorals of the Genus Pachyclavularia

Marine Drugs, 2017
In this paper, we reviewed natural compounds isolated from octocorals belonging to the genus Pachyclavularia, including 20 cembrane-, 39 briarane-, and eight briarellin-related diterpenoids, and one secosterol.
Yu-Chia Chang, Jyh-Horng Sheu, Yang-Chang Wu, Ping-Jyun Sung   +3 more
doaj   +1 more source