Twist1 Suppresses Cementoblast Differentiation
The transcription factor Twist1 is known to be closely associated with the formation of bone by mesenchymal stem cells and osteoblasts; however, the role of Twist1 in cementogenesis has not yet been determined.
Jung-Sun Moon +5 more
doaj +1 more source
Genetic and pharmacologic modulation of cementogenesis via pyrophosphate regulators
Pyrophosphate (PPi) serves as a potent and physiologically important regulator of mineralization, with systemic and local concentrations determined by several key regulators, including: tissue-nonspecific alkaline phosphatase (ALPL gene; TNAP protein), the progressive ankylosis protein (ANKH; ANK), and ectonucleotide pyrophosphatase/phosphodiesterase 1
E Y, Chu +14 more
openaire +3 more sources
Effects of different powder to liquid ratios on the push out bond strength of CEM cement on simulated perforations in the furcal area [PDF]
Proper bond strength to dentin is one of the properties of biomaterials used for therapeutic purposes such as repair of furcal perforations. The aim of the present study to evaluate the effects of different powder to liquid ratios of Calcium-enriched ...
Frough-Reyhani, Mohammad +3 more
core +1 more source
Deficiency of Trps1 in Cementoblasts Impairs Cementogenesis and Tooth Root Formation. [PDF]
Cementum is the least studied of all mineralized tissues and little is known about mechanisms regulating its formation. Therefore, the goal of this study was to provide new insights into the transcriptional regulation of cementum formation by determining the consequences of the deficiency of the Trps1 transcription factor in cementoblasts.
Fujikawa K +6 more
europepmc +3 more sources
Background and objective There is evidence from previous studies that pregnancies and diseases are recorded in the tooth cementum. This study aims to assess the degree of concordance between signals based on irregular incremental lines (ILs) and reported
Gabriela Mani-Caplazi +3 more
doaj +2 more sources
The cytotoxic evaluation of mineral trioxide aggregate and bioaggregate in the subcutaneous connective tissue of rats [PDF]
Objectives: The purpose of this study was to evaluate and compare the cytotoxic effects of ProRoot MTA and DiaRoot BA, a bioceramic nanoparticulate cement, on subcutaneous rat tissue.
Acar, Gözde +5 more
core +1 more source
Amelogenin Peptide Extract Increases Differentiation and Angiogenic and Local Factor Production and Inhibits Apoptosis in Human Osteoblasts [PDF]
Enamel matrix derivative (EMD), a decellularized porcine extracellular matrix (ECM), is used clinically in periodontal tissue regeneration. Amelogenin, EMD’s principal component, spontaneously assembles into nanospheres in vivo, forming an ECM complex ...
Almaguer-Flores, Argelia +6 more
core +2 more sources
Oral and craniofacial manifestations and two novel missense mutations of the NTRK1 gene identified in the patient with congenital insensitivity to pain with anhidrosis. [PDF]
Congenital insensitivity to pain with anhidrosis (CIPA) is a rare inherited disorder of the peripheral nervous system resulting from mutations in neurotrophic tyrosine kinase receptor 1 gene (NTRK1), which encodes the high-affinity nerve growth factor ...
Li Gao +11 more
doaj +1 more source
Interaction of enamel matrix proteins with human periodontal ligament cells [PDF]
Dorothy Hodgkin Postgraduate Award for research studies (jointly funded by the Engineering and Physical Sciences Research Council, UK, and by Institut Straumann) and the Research Discretionary Funds of the Periodontology Unit, UCL Eastman Dental ...
A Cate Ten +34 more
core +2 more sources
Dental cementum reviewed: development, structure, composition, regeneration and potential functions
This article reviews developmental and structural characteristics of cementum, a unique avascular mineralized tissue covering the root surface that forms the interface between root dentin and periodontal ligament. Besides describing the types of cementum
Patricia Furtado Gonçalves +5 more
doaj +1 more source

