Results 1 to 10 of about 3,373 (167)

The Immune Cell Atlas of "Longevity Molecular Tag": Identification of Principal Immune Cell Subsets and Their Underlying Molecular Regulatory Mechanisms. [PDF]

Aging Cell
This study aims to develop an immune cell atlas of the “Longevity Molecular Tags” by employing the Scissor algorithm to identify key immune cell subsets associated with longevity phenotypes. Subsequently, the underlying immune molecular mechanisms contributing to the longevity‐associated immune cell subsets were investigated through differential gene ...
Zhang Z, Su H, Fu S, Ji F, Liang L, Song W, Hu C, Wei L, Long E, Lin Y, Ni X.   +10 more
europepmc   +2 more sources

Case Report: endoscopic microvascular decompression for trigeminal neuralgia in a centenarian: a landmark case with 5-year follow-up [PDF]

Frontiers in Surgery
BackgroundEndoscopic Microvascular Decompression (E-MVD) is a well-established effective treatment option for trigeminal neuralgia (TN). However, its application in ultra-elderly patients, particularly centenarians, has never been documented.Case ...
Xuhao Fang, Feng Tang, Yao Deng, Yue Zhou, Weidong Gu, Renling Mao   +5 more
doaj   +2 more sources

Edentulousness and the Likelihood of Becoming a Centenarian: Longitudinal Observational Study [PDF]

JMIR Aging
BackgroundIn recent decades, the global life expectancy has risen notably to approximately 73.5 years worldwide, coinciding with a rapid growth in the older adult population, which presents a significant public health challenge in promoting healthy aging
Xindi Wei, Longfei Zhuang, Yuan Li, Junyu Shi, Yijie Yang, Hongchang Lai, Beilei Liu   +6 more
doaj   +2 more sources

Relationships Between Hair Chemical Elements and Nutritional Status in Oldest-Old and Centenarian Populations

Journal of Multidisciplinary Healthcare, 2023
Qiao Zhu,1,* Qingkai Zhao,2,* Ping Ping,3,* Qian Zhang,4,* Li Gong,5 Long Feng,6 Yali Zhao,1 Shihui Fu7,8 1Central Laboratory, Hainan Hospital of Chinese People’s Liberation Army General Hospital, Sanya, People’s Republic of China ...
Zhu Q, Zhao Q, Ping P, Zhang Q, Gong L, Feng L, Zhao Y, Fu S   +7 more
exaly   +2 more sources

Nutrition and longevity – diet in centenarians [PDF]

Journal of Translational Medicine
Background Nutrition plays a central role in the biological mechanisms that shape aging, health span, and longevity. Micronutrients—including vitamins, trace elements, and polyphenols—support genomic stability, mitochondrial integrity, and antioxidant ...
Evelyn Frias-Toral, Claudia Reytor-González, Giuseppe Annunziata, Ludovica Verde, Emilia Jimenez-Flores, Keya Sen, Martina Galasso, Giovanna Muscogiuri, Daniel Simancas-Racines, Maria Dalamaga, Luigi Barrea   +10 more
doaj   +2 more sources

Effects of physical disability and widowhood on the survival of centenarians: a 7-year follow-up of CHCCS centenarians [PDF]

Frontiers in Aging
BackgroundCentenarians, being at the end of their life span, are particularly vulnerable to various health risks. Multiple factors can influence their survival and targeted intervention on these factors may promote healthy aging.PurposeThis study aims to
Songmei Han, Songmei Han, Dongxu Zhao, Jianbo Wu, Mingzhi Shen, Fei Hua   +5 more
doaj   +2 more sources

Mutant Single Nucleotide Polymorphism rs189037 in Ataxia-Telangiectasia Mutated Gene Is Significantly Associated With Ventricular Wall Thickness and Human Lifespan

Frontiers in Cardiovascular Medicine, 2021
In the current study, we aimed to determine the association of single nucleotide polymorphism rs189037 in ataxia-telangiectasia mutated (ATM) gene with cardiac structure and human longevity. Based on the China Hainan Centenarian Cohort Study performed in
Shihui Fu, Shihui Fu, Jianqiu Hu, Xiaoping Chen, Bo Li, Hongjuan Shun, Juelin Deng, Yujie Zhang, Yao Yao, Yao Yao, Yali Zhao   +10 more
doaj   +1 more source

A case of successful thoracic endovascular aneurysm repair in a 106-year-old female

Indian Journal of Vascular and Endovascular Surgery, 2021
As the population ages, the average age of patients is expected to rise. Here, we describe a successful case of thoracic endovascular aneurysm repair (TEVAR) performed in a 106-year-old female.
Kanako Kobayashi, Ayaka Yu, Naoki Fujimura, Satoshi Otsubo   +3 more
doaj   +1 more source

Female Fertility Has a Negative Relationship With Longevity in Chinese Oldest-Old Population: A Cross-Sectional Study

Frontiers in Endocrinology, 2021
BackgroundDespite research efforts in this field for more than a century, the relationship between female fertility and longevity is unclear. This study was designed to investigate this relationship in Chinese oldest-old population.MethodsThe China ...
Qiao Zhu, Shihui Fu, Qian Zhang, Jinwen Tian, Yali Zhao, Yao Yao, Yao Yao   +6 more
doaj   +1 more source

The relationship between depressive mood and subjective health in centenarians and near-centenarians: a cross-sectional study from Korean centenarian cohort

The Aging Male, 2023
Background With the rapid increase in population longevity, more clinical attention is being paid to the overall health of long-lived people, especially centenarians.
Min Jhon, Min-Ho Shin, Kyung Chul Yoon, Jeong-Sun Kim, Jeonghwa Lee, Kwangsung Park, Sang Chul Park   +6 more
doaj   +1 more source