Results 61 to 70 of about 3,373 (167)

RBFOX1 association with age at onset of Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Genetic contributors to early onset Alzheimer's disease (AD) beyond APP and PSEN1/2 remain unknown. Identifying novel loci may reveal disease mechanisms and therapeutic targets. We investigated genetic variants influencing age at onset in early onset families from the Long‐Life Family Study (LLFS).
Laura Xicota, Rong Cheng, Stacy L. Andersen, Joseph M. Zmuda, Mary Wojczynski, Mary F. Feitosa, Joseph Bradley, Carlos Cruchaga, Alex G. Contreras, Timothy J. Hohman, Dolly Reyes‐Dumeyer, Badri V. Vardarajan, Stephanie Cosentino, Richard Mayeux, Joseph H. Lee, Sandra Barral, the Long‐Life Family Study (LLFS), Estudio Familiar de Influencia Genetica en Alzheimer (EFIGA), and The National Institute on Aging Alzheimer's Disease Family Based Study (NIA‐LOAD FBS)   +18 more
wiley   +1 more source

The Role of the Gut Microbiome in the Complex Network of Frailty Syndrome and Associated Comorbidities in Aging

Aging Cell, Volume 25, Issue 2, February 2026.
This study analyzed gut microbiota in older adults with and without Frailty Syndrome by 16S rRNA gene sequencing and metagenomics. Frailty was associated with altered microbial composition, metabolic functions, and increased antimicrobial resistance, whereas non‐frail individuals showed healthier profiles.
Ana Barberá, Rosario Ortolá, Mercedes Sotos‐Prieto, Fernando Rodríguez‐Artalejo, Andrés Moya, Susana Ruiz‐Ruiz   +5 more
wiley   +1 more source

New estimates of Australia’s centenarian population

International Journal of Population Data Science, 2018
Introduction: The population of Australia at the very highest ages is growing rapidly, like that of many countries. But official population estimates at these ages are of lower quality than those at younger ages, a problem shared by many countries which ...
Tom Wilson, Wilma Terblanche
doaj   +1 more source

Red-Wine Gene Networks Linked to Exceptional Longevity in Humans

Biomolecules
Despite the health concerns regarding alcohol and its link to cancer, moderate consumption of red wine has been associated with healthy aging and longevity, defined as up to one drink per day for women and two drinks per day for men (approximately 142 mL
Patricia Lacayo, Alexandria Martignoni, Kenneth Park, Christianne Castro, Shin Murakami   +4 more
doaj   +1 more source

Idea

World Nutrition, 2015
Fred Kummerow The centenarian ...
Fred A Kummerow
doaj  

Nutritional and health claims compliance of olive oils produced from centenarian olive trees

Cogent Food & Agriculture
This work examined whether centenarian trees could be a source of virgin olive oil (VOO) that accomplishes nutritional and health claims regarding unsaturated fatty acids (UFA), tocopherols and phenolic compounds (tyrosol and hydroxytyrosol derivatives).
Leticia Bortoluzzi, Susana Casal, Rebeca Cruz, António M. Peres, Paula Baptista, Nuno Rodrigues   +5 more
doaj   +1 more source

Lessons for Successful Aging: A Centenarian's Lifestyle in a Mexican Community of Aging

Anthropology & Aging, 2015
It is clearly established in the scientific literature that an appropriate lifestyle is key to achieving and maintaining optimum health and functional status in old age.
José Azoh Barry
doaj   +1 more source

Demographic characteristics of Sardinian centenarian genealogies: Preliminary results of the AKeA2 study

Demographic Research, 2015
Objective: This article provides an overview of the AKeA2 study, with a particular focus on data collection concerning family genealogies of the Sardinian centenarians and controls, and on the quality of these data.
Rosa Maria Lipsi, Graziella Caselli, Lucia Pozzi, Giovannella Baggio, Ciriaco Carru, Claudio Franceschi, James W. Vaupel, Luca Deiana   +7 more
doaj   +1 more source

Associations Between Complement C4, Habitual Constipation, and Sleep Disturbance in Oldest-Old and Centenarian Chinese Adults

Journal of Inflammation Research
Zhigao Sun,1,* Yan Nie,2,* Jianqiu Pei,3,* Ming Gao,4,* Zhe Luan,5,* Yali Zhao,6 Zhaoxing Li,7 Shihui Fu8,9 1Traditional Chinese Medicine Department, Hainan Hospital of Chinese People’s Liberation Army General Hospital, Sanya, People ...
Sun Z, Nie Y, Pei J, Gao M, Luan Z, Zhao Y, Li Z, Fu S   +7 more
doaj  

“Positive biology”: the centenarian lesson

Immunity & Ageing, 2012
The extraordinary increase of the elderly in developed countries underscore the importance of studies on ageing and longevity and the need for the prompt spread of knowledge about ageing in order to satisfactorily decrease the medical, economic and ...
Caruso Calogero, Passarino Giuseppe, Puca Annibale, Scapagnini Giovanni   +3 more
doaj   +1 more source