Results 1 to 10 of about 3,002,143 (356)

DNA methylation-based classification of central nervous system tumours. [PDF]

Nature, 2018
Accurate pathological diagnosis is crucial for optimal management of patients with cancer. For the approximately 100 known tumour types of the central nervous system, standardization of the diagnostic process has been shown to be particularly challenging-
Aronica, Eleonora, Becker, Albert, Benner, Axel, Beschorner, Rudi, Bewerunge-Hudler, Melanie, Bjerkvig, Rolf, Braczynski, Anne K, Brehmer, Stefanie, Brück, Wolfgang, Calaminus, Gabriele, Capper, David, Chavez, Lukas, Coras, Roland, Cryan, Jane, Deckert, Martina, Dohmen, Hildegard, Driever, Pablo Hernáiz, Engel, Nils W, Farrell, Michael, Fischer, Roger, Fleischhack, Gudrun, Frank, Stephan, Frühwald, Michael C, Garvalov, Boyan K, Geisenberger, Christoph, Giangaspero, Felice, Gnekow, Astrid, Gottardo, Nicholas G, Haberler, Christine, Hans, Volkmar, Hansford, Jordan R, Harter, Patrick N, Hench, Jürgen, Heppner, Frank, Hewer, Ekkehard, Hofer, Silvia, Hovestadt, Volker, Huang, Kristin, Hänggi, Daniel, Hölsken, Annett, Jones, Chris, Jones, David TW, Jouvet, Anne, Kannan, Kasthuri, Keohane, Catherine, Ketter, Ralf, Khatib, Ziad, Koch, Arend, Koelsche, Christian, Kohlhof, Patricia, Kramm, Christof M, Kratz, Annekathrin, Kristensen, Bjarne W, Kulozik, Andreas, Lechner, Matt, Lindenberg, Kerstin, Lohmann, Dietmar, Lopes, Beatriz, Mawrin, Christian, Milde, Till, Monoranu, Camelia-Maria, Mueller, Wolf, Mühleisen, Helmut, Müller, Hermann L, Olar, Adriana, Pages, Melanie, Pajtler, Kristian W, Perry, Arie, Plate, Karl H, Pohl, Ute, Preusser, Matthias, Prinz, Marco, Reuss, David E, Rodriguez, Fausto J, Rozsnoki, Stephanie, Rushing, Elisabeth, Rutkowski, Stefan, Sahm, Felix, Scheurlen, Wolfram, Schick, Matthias, Schittenhelm, Jens, Schrimpf, Daniel, Schweizer, Leonille, Seiz-Rosenhagen, Marcel, Selt, Florian, Serrano, Jonathan, Sill, Martin, Staszewski, Ori, Stichel, Damian, Sturm, Dominik, Temming, Petra, Tippelt, Stephan, Tsirigos, Aristotelis, Varlet, Pascale, von Hoff, Katja, Wani, Khalida, Wefers, Annika K, Witt, Hendrik, Witt, Olaf, Zapatka, Marc   +99 more
core   +3 more sources

Brain and other central nervous system tumor statistics, 2021

Ca-A Cancer Journal for Clinicians, 2021
Brain and other central nervous system (CNS) tumors are among the most fatal cancers and account for substantial morbidity and mortality in the United States.
Carol Kruchko, Kristin A Waite, Kimberly D Miller   +2 more
exaly   +2 more sources

The 2021 WHO Classification of Tumors of the Central Nervous System: a summary.

Neuro-Oncology, 2021
The fifth edition of the WHO Classification of Tumors of the Central Nervous System (CNS), published in 2021, is the sixth version of the international standard for the classification of brain and spinal cord tumors.
D. Louis, A. Perry, P. Wesseling, D. Brat, I. Cree, D. Figarella-Branger, C. Hawkins, H. Ng, S. Pfister, G. Reifenberger, R. Soffietti, A. von Deimling, D. Ellison   +12 more
semanticscholar   +1 more source

Brain and Retinal Abnormalities in the 5xFAD Mouse Model of Alzheimer's Disease at Early Stages

Frontiers in Neuroscience, 2021
One of the major challenges in treating Alzheimer's disease (AD) is its early diagnosis. Increasing data from clinical and animal research indicate that the retina may facilitate an early diagnosis of AD. However, a previous study on the 5xFAD (a fast AD
Mengrong Zhang, Liting Zhong, Xiu Han, Guoyin Xiong, Di Xu, Sensen Zhang, Haiyang Cheng, Kin Chiu, Kin Chiu, Ying Xu, Ying Xu, Ying Xu   +11 more
doaj   +1 more source

CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2015-2019.

Neuro-Oncology, 2022
The Central Brain Tumor Registry of the United States (CBTRUS), in collaboration with the Centers for Disease Control and Prevention and the National Cancer Institute, is the largest population-based registry focused exclusively on primary brain and ...
Q. Ostrom, M. Price, C. Neff, G. Cioffi, K. Waite, C. Kruchko, J. Barnholtz-Sloan   +6 more
semanticscholar   +1 more source

Effects of the mGlu2/3 receptor agonist LY379268 on two models of disturbed auditory evoked brain oscillations in mice

Translational Psychiatry, 2023
Cognitive impairment is a core feature of schizophrenia and is poorly addressed by currently available medication. This is partly because the underlying circuits are insufficiently understood, and available animal models for brain dysfunction do not ...
Oana-Daniela Dormann, Niklas Schuelert, Holger Rosenbrock   +2 more
doaj   +1 more source

Redox-neutral and metal-free synthesis of 3-(arylmethyl)chroman-4-ones via visible-light-driven alkene acylarylation

Frontiers in Chemistry, 2022
A metal- and aldehyde-free visible-light-driven photoredox-neutral alkene acylarylation with readily available cyanoarenes is described. A variety of 3-(arylmethyl)chroman-4-ones (i.e., homoisoflavonoids) and analogs are efficiently synthesized with good
Yan Ding, Shengjiao Yu, Man Ren, Ji Lu, Qiang Fu, Zhijie Zhang, Qin Wang, Jun Bai, Na Hao, Lin Yang, Siping Wei, Dong Yi, Jun Wei   +12 more
doaj   +1 more source

HIF-1α participates in secondary brain injury through regulating neuroinflammation

Translational Neuroscience, 2023
A deeper understanding of the underlying biological mechanisms of secondary brain injury induced by traumatic brain injury (TBI) will greatly advance the development of effective treatments for patients with TBI. Hypoxia-inducible factor-1 alpha (HIF-1α)
Xu Xiaojian, Yang Mengshi, Zhang Bin, Dong Jinqian, Zhuang Yuan, Ge Qianqian, Niu Fei, Liu Baiyun   +7 more
doaj   +1 more source

Brainstem syndrome at onset is related to an early MS diagnosis in Peru: A national referral center cohort

Heliyon, 2021
Background: MS is unpredictable regarding clinical symptoms; however, certain symptoms represent the preferred localization of white matter lesions such as brainstem, spinal cord; or optic nerve.
César Caparó-Zamalloa, Sheila Castro-Suarez, Jaqueline Cortez-Escalante, Wilfor Aguirre-Quispe, Erik Guevara-Silva, Victor Osorio-Marcatinco, María Meza-Vega   +6 more
doaj   +1 more source

CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2014-2018.

Neuro-Oncology, 2021
The Central Brain Tumor Registry of the United States (CBTRUS), in collaboration with the CDC and NCI, is the largest population-based registry focused exclusively on primary brain and other central nervous system (CNS) tumors in the United States (US ...
Q. Ostrom, G. Cioffi, K. Waite, C. Kruchko, J. Barnholtz-Sloan   +4 more
semanticscholar   +1 more source