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Central nervous system physiology [PDF]

open access: yesClinical Neurophysiology, 2021
This is the second chapter of the series on the use of clinical neurophysiology for the study of movement disorders. It focusses on methods that can be used to probe neural circuits in brain and spinal cord. These include use of spinal and supraspinal reflexes to probe the integrity of transmission in specific pathways; transcranial methods of brain ...
John Rothwell   +8 more
openaire   +8 more sources

Immunology and the Central Nervous System [PDF]

open access: yesClinical and Developmental Immunology, 2013
We are pleased to announce the publication of this special issue in the journal “Clinical and Developmental Immunology.” We are happy to perceive the growing interest, from a wide range of scientists, regarding the peculiar intercommunication between the immune system and the central nervous system (CNS).
Carlos Barcia   +3 more
openaire   +9 more sources

Modelling the spatial organization of cell proliferation in the developing central nervous system [PDF]

open access: yesarXiv, 2010
How far is neuroepithelial cell proliferation in the developing central nervous system a deterministic process? Or, to put it in a more precise way, how accurately can it be described by a deterministic mathematical model? To provide tracks to answer this question, a deterministic system of transport and diffusion partial differential equations, both ...
Clairambault, Jean   +5 more
arxiv   +6 more sources

Brain and Retinal Abnormalities in the 5xFAD Mouse Model of Alzheimer's Disease at Early Stages

open access: yesFrontiers in Neuroscience, 2021
One of the major challenges in treating Alzheimer's disease (AD) is its early diagnosis. Increasing data from clinical and animal research indicate that the retina may facilitate an early diagnosis of AD. However, a previous study on the 5xFAD (a fast AD
Mengrong Zhang   +11 more
doaj   +1 more source

Central Nervous System Tumors [PDF]

open access: yes, 2022
Though the treatment of central nervous system (CNS) tumors has been challenging, new advances have helped us better understand the molecular and genetic makeup of many tumor types, and new chemotherapies and immunotherapies have extended survival in ...

core   +1 more source

Effects of the mGlu2/3 receptor agonist LY379268 on two models of disturbed auditory evoked brain oscillations in mice

open access: yesTranslational Psychiatry, 2023
Cognitive impairment is a core feature of schizophrenia and is poorly addressed by currently available medication. This is partly because the underlying circuits are insufficiently understood, and available animal models for brain dysfunction do not ...
Oana-Daniela Dormann   +2 more
doaj   +1 more source

HIF-1α participates in secondary brain injury through regulating neuroinflammation

open access: yesTranslational Neuroscience, 2023
A deeper understanding of the underlying biological mechanisms of secondary brain injury induced by traumatic brain injury (TBI) will greatly advance the development of effective treatments for patients with TBI. Hypoxia-inducible factor-1 alpha (HIF-1α)
Xu Xiaojian   +7 more
doaj   +1 more source

Redox-neutral and metal-free synthesis of 3-(arylmethyl)chroman-4-ones via visible-light-driven alkene acylarylation

open access: yesFrontiers in Chemistry, 2022
A metal- and aldehyde-free visible-light-driven photoredox-neutral alkene acylarylation with readily available cyanoarenes is described. A variety of 3-(arylmethyl)chroman-4-ones (i.e., homoisoflavonoids) and analogs are efficiently synthesized with good
Yan Ding   +12 more
doaj   +1 more source

MPs-ACT, an Assay to Evaluate the Procoagulant Activity of Microparticles

open access: yesClinical and Applied Thrombosis/Hemostasis, 2023
The procoagulant effect of microparticles (MPs) contributes to hypercoagulability-induced thrombosis. We provide preliminary findings of the MPs-Activated Clotting Time (MPs-ACT) assay to determine the procoagulant activity of MPs.
Yalong Gao PhD   +14 more
doaj   +1 more source

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