Results 11 to 20 of about 1,988,517 (312)

miR-19a/b promote EMT and proliferation in glioma cells via SEPT7-AKT-NF-κB pathway

open access: yesMolecular Therapy: Oncolytics, 2021
miR-19a/b belong to the miR-17-92 family. We have demonstrated previously that miR-19a/b are overexpressed in glioma and glioma cell lines. However, the role of miR-19a/b in glioma remains unclear.
Weihan Wang   +6 more
doaj   +1 more source

TERT expression is susceptible to BRAF and ETS-factor inhibition in BRAF V600E /TERT promoter double-mutated glioma

open access: yesActa Neuropathologica Communications, 2019
The BRAF gene and the TERT promoter are among the most frequently altered genomic loci in low-grade (LGG) and high-grade-glioma (HGG), respectively.
Lisa Gabler   +19 more
doaj   +1 more source

Somatostatin contributes to long-term potentiation at excitatory synapses onto hippocampal somatostatinergic interneurons

open access: yesMolecular Brain, 2021
Somatostatin-expressing interneurons (SOM-INs) are a major subpopulation of GABAergic cells in CA1 hippocampus that receive excitation from pyramidal cells (PCs), and, in turn, provide feedback inhibition onto PC dendrites.
Anne-Sophie Racine   +3 more
doaj   +1 more source

Tertiary lymphoid organs in central nervous system autoimmunity [PDF]

open access: yes, 2016
Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation in the central nervous system (CNS), which results in permanent neuronal damage and substantial disability in patients.
Mitsdoerffer, M., Peters, A.
core   +1 more source

Inhibition of neutrophil extracellular trap formation attenuates NLRP1-dependent neuronal pyroptosis via STING/IRE1α pathway after traumatic brain injury in mice

open access: yesFrontiers in Immunology, 2023
IntroductionIncreased neutrophil extracellular trap (NET) formation has been reported to be associated with cerebrovascular dysfunction and neurological deficits in traumatic brain injury (TBI).
Yiyao Cao   +45 more
doaj   +1 more source

Use of a compact high-definition two-dimensional exoscope in surgical treatment of large vestibular schwannoma

open access: yesChinese Medical Journal, 2020
. Background:. Extra-corporeal video telescope operating monitor system provides a necessary instrument to perform high-precision neurosurgical procedures that could substitute or supplement the traditional surgical microscope.
Xin Chen   +6 more
doaj   +1 more source

Observation of experimental lathyrism in the rat [PDF]

open access: yes, 1959
The clinical manifestations, roentgenologic studies, and histopathologic findings of the central nervous system of rats with induced lathyrism were described.
Lee, HUN Jae
core   +1 more source

The various routes to functional regeneration in the central nervous system [PDF]

open access: yes, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Echeverri, K.
Echeverri, Karen
core   +1 more source

Immunohistochemical demonstration of specific antigens in the human brain fixed in zinc-ethanol-formaldehyde

open access: yesEuropean Journal of Histochemistry, 2015
Tissue fixation is critical for immunohistochemistry. Recently, we developed a zinc-ethanol-formalin fixative (ZEF), and the present study was aimed to assess the applicability of the ZEF for the human brain histology and immunohistochemistry and to ...
D.E. Korzhevskii   +3 more
doaj   +1 more source

Effects of Tocilizumab Therapy on Circulating B Cells and T Helper Cells in Patients With Neuromyelitis Optica Spectrum Disorder

open access: yesFrontiers in Immunology, 2021
Tocilizumab, a humanized anti-IL-6 receptor monoclonal antibody, showed its therapeutic efficacy on neuromyelitis optica spectrum disorder (NMOSD).
Ye Liu   +12 more
doaj   +1 more source

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