Results 21 to 30 of about 1,988,517 (312)

NLRP1 Inflammasomes: A Potential Target for the Treatment of Several Types of Brain Injury

Frontiers in Immunology, 2022
NOD-like receptor (NLR) family pyrin domain-containing 1 (NLRP1) is a member of the NLR family. The NLRP1 inflammasome consists of the NLRP1 protein, the adaptor protein apoptosis-associated speck-like protein containing a CARD domain, and the effector ...
Liang Mi, Liang Mi, Xiaobin Min, Xiaobin Min, Yan Chai, Jianning Zhang, Jianning Zhang, Xin Chen, Xin Chen   +8 more
doaj   +1 more source

MicroRNA-23a promotes myelination in the central nervous system. [PDF]

, 2013
Demyelinating disorders including leukodystrophies are devastating conditions that are still in need of better understanding, and both oligodendrocyte differentiation and myelin synthesis pathways are potential avenues for developing treatment ...
Fu, Ying-Hui, Heng, Mary Y, Huang, Yong, Lin, Shu-Ting, Ptácek, Louis J, Zhang, Luoying   +5 more
core   +2 more sources

DNA Methylation Associates With Clinical Courses of Atypical Meningiomas: A Matched Case–Control Study

Frontiers in Oncology, 2022
BackgroundAccounting for 15–20% of all meningiomas, WHO grade II meningiomas represent an intermediate group regarding risk of tumor recurrence. However, even within this subgroup varying clinical courses are observed with potential occurrence of ...
Matthias Millesi, Matthias Millesi, Alice Senta Ryba, Alice Senta Ryba, Johannes A. Hainfellner, Johannes A. Hainfellner, Thomas Roetzer, Thomas Roetzer, Anna Sophie Berghoff, Anna Sophie Berghoff, Matthias Preusser, Matthias Preusser, Gerwin Heller, Gerwin Heller, Erwin Tomasich, Erwin Tomasich, Felix Sahm, Felix Sahm, Karl Roessler, Karl Roessler, Stefan Wolfsberger, Stefan Wolfsberger   +21 more
doaj   +1 more source

Endoplasmic Reticulum Stress-Associated Neuronal Death and Innate Immune Response in Neurological Diseases

Frontiers in Immunology, 2022
Neuronal death and inflammatory response are two common pathological hallmarks of acute central nervous system injury and chronic degenerative disorders, both of which are closely related to cognitive and motor dysfunction associated with various ...
Mingming Shi, Mingming Shi, Mingming Shi, Yan Chai, Yan Chai, Jianning Zhang, Jianning Zhang, Jianning Zhang, Xin Chen, Xin Chen, Xin Chen   +10 more
doaj   +1 more source

Primary central nervous system lymphoma [PDF]

, 2008
O linfoma primário do sistema nervoso central (LPSNC) é um linfoma extralinfonodal que, ao diagnóstico, encontra-se restrito ao parênquima cerebral, às meninges e/ou cordão espinhal e/ou olhos.
BEITLER, Beatriz, BELLESSO, Marcelo, BIZZETTO, Renata, CHAMONE, Dalton A. S., PEREIRA, Juliana, PRACCHIA, Luis Fernando   +5 more
core   +2 more sources

Women in the field of multiple sclerosis: How they contributed to paradigm shifts

Frontiers in Molecular Neuroscience, 2023
History is full of women who made enormous contributions to science. While there is little to no imbalance at the early career stage, a decreasing proportion of women is found as seniority increases.
Andreia Barateiro, Andreia Barateiro, Catarina Barros, Maria V. Pinto, Ana Rita Ribeiro, Ainhoa Alberro, Ainhoa Alberro, Adelaide Fernandes, Adelaide Fernandes   +8 more
doaj   +1 more source

Ontogeny of synaptophysin and synaptoporin in the central nervous system [PDF]

, 1993
The expression of the synaptic vesicle antigens synaptophysin (SY) and synaptoporin (SO) was studied in the rat striatum, which contains a nearly homogeneous population of GABAergic neurons. In situ hybridization revealed high levels of SY transcripts in
B. Marquèze-Pouey, Bergmann, Betz, D. Grabs, Goldman-Rakic, Graybiel, H. Betz, Heimer, Hsu, I. Reisert, Iñiguez, Jahn, Jahn, Kita, Knaus, Lahr, Lauder, Leube, Lindefors, M. Bergmann, M. Gratzl, Marquèze-Pouey, Mugnaini, Newman-Gage, Olson, P. Knaus, Reiner, Reisert, Smith, Specht, Specht, Südhof, Thomas, Vernier, W. Ovtscharoff, Wiedenmann, Wilson   +36 more
core   +1 more source

EGFR-vIII downregulated H2AZK4/7AC though the PI3K/AKT-HDAC2 axis to regulate cell cycle progression

Clinical and Translational Medicine, 2020
Background The EGFR-vIII mutation is the most common malignant event in GBM. Epigenetic reprogramming in EGFR-activated GBM has recently been suggested to downregulate the expression of tumour suppressor genes.
Hongyu Zhao, Yunfei Wang, Chao Yang, Junhu Zhou, Lin Wang, Kaikai Yi, Yansheng Li, Qixue wang, Jin Shi, Chunsheng Kang, Liang Zeng   +10 more
doaj   +1 more source

Exploration of cerebral vasospasm from the perspective of microparticles

Frontiers in Neuroscience, 2022
Cerebral vasospasm is a frequently encountered clinical problem, especially in patients with traumatic brain injury and subarachnoid hemorrhage. Continued cerebral vasospasm can cause cerebral ischemia, even infarction and delayed ischemic neurologic ...
Yalong Gao, Kai Li, Xiaotian Li, Qifeng Li, Jiwei Wang, Jiwei Wang, Shu Zhang, Jianning Zhang   +7 more
doaj   +1 more source

Confocal analysis of nervous system architecture in direct-developing juveniles of Neanthes arenaceodentata (Annelida, Nereididae) [PDF]

, 2010
Background: Members of Family Nereididae have complex neural morphology exemplary of errant polychaetes and are leading research models in the investigation of annelid nervous systems.
Jacobs, David K., Valencia, Jonathan E., Winchell, Christopher J.   +2 more
core   +5 more sources