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Antigen presentation for central tolerance induction
Nature Reviews ImmunologyThe extent of central T cell tolerance is determined by the diversity of self-antigens that developing thymocytes 'see' on thymic antigen-presenting cells (APCs). Here, focusing on insights from the past decade, we review the functional adaptations of medullary thymic epithelial cells, thymic dendritic cells and thymic B cells for the purpose of ...
Ludger, Klein, Elisabetta, Petrozziello
openaire +2 more sources
GDF15 Is an Inflammation-Induced Central Mediator of Tissue Tolerance
Cell, 2019Harding H Luan +2 more
exaly
How defects in central tolerance impinge on a deficiency in regulatory T cells
Proceedings of the National Academy of Sciences of the United States of America, 2005Zhibin Chen +2 more
exaly
Central Tolerance to Tissue-specific Antigens Mediated by Direct and Indirect Antigen Presentation
Journal of Experimental Medicine, 2004Michael J Bevan, Bevan Michael J
exaly
Big impact of microRNAs on central B cell tolerance
Nature Immunology, 2016Eric Meffre, Meffre Eric
exaly

