Results 51 to 60 of about 1,388,516 (221)

Harnessing complex light-matter interactions for point-of-care nano-optical biosensing

Advances in Physics: X
Recent advancements in nanoscale physics have resulted in a paradigm shift towards point-of-care (POC) complex healthcare diagnostics, enabling real-time biomolecular detection.
Vishal Chaudhary, Harsh Sable, Pradeep Bhadola   +2 more
doaj   +1 more source

Some of the snags of interdisciplinarity: from life forms into form of life studies [PDF]

, 2004
In this paper I look at some central problems, which have been puzzling me in my PhD research, when applying an interdisciplinary approach to data. My thesis is about the reader’s identity construction in the English-language newspapers in Portugal ...
mattos-parreira, merja
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

NLO friction in symmetry restoring phase transitions

Journal of High Energy Physics
Interactions between bubbles/domain walls and the surrounding medium are a topic of active research, particularly as they apply to friction effects on accelerated expansion during first-order phase transitions.
Aleksandr Azatov, Giulio Barni, Rudin Petrossian-Byrne   +2 more
doaj   +1 more source

The power of perturbation theory

Journal of High Energy Physics, 2017
We study quantum mechanical systems with a discrete spectrum. We show that the asymptotic series associated to certain paths of steepest-descent (Lefschetz thimbles) are Borel resummable to the full result.
Marco Serone, Gabriele Spada, Giovanni Villadoro   +2 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Diffractive semi-hard production of a $$J/\psi $$ J / ψ or a $$\Upsilon $$ Υ from single-parton fragmentation plus a jet in hybrid factorization

European Physical Journal C: Particles and Fields, 2022
We investigate the inclusive hadroproduction of a heavy quarkonium ( $$J/\psi $$ J / ψ or $$\Upsilon $$ Υ ), in association with a light-flavored jet, as a testing ground for the semi-hard regime of QCD.
Francesco Giovanni Celiberto, Michael Fucilla   +1 more
doaj   +1 more source

Direct measurement of dark matter halo ellipticity from two-dimensional lensing shear maps of 25 massive clusters [PDF]

, 2010
We present new measurements of dark matter distributions in 25 X-ray luminous clusters by making a full use of the two-dimensional (2D) weak lensing signals obtained from high-quality Subaru/Suprime-Cam imaging data.
Adami, Allgood, Bahcall, Bahcall, Bardeau, Bartelmann, Bartelmann, Bertin, Borgani, Bradač, Broadhurst, Broadhurst, Buote, Buote, Böhringer, Choi, Clowe, Corless, Cypriano, Dahle, De Theije, Deb, Dodelson, Ebeling, Ebeling, Eke, Evans, Flores, Gavazzi, Graham P. Smith, Hamana, Hennawi, Henry, Henry, Ho, Hoekstra, Hoekstra, Ilbert, Jee, Jing, Kaiser, Kaiser, Kasliwal, Kasun, Katayama, Kawahara, Kazantzidis, Keeton, Kitayama, Kneib, Koester, Kolokotronis, Komatsu, Koopmans, Lee, Lin, Mahdavi, Mahdavi, Mandelbaum, Mandelbaum, Mandelbaum, Mandelbaum, Mantz, Masahiro Takada, Masamune Oguri, McMillan, Medezinski, Miralda Escude, Miyazaki, Mohr, Navarro, Navarro, Nobuhiro Okabe, Oguri, Oguri, Oguri, Oguri, Oguri, Okabe, Okabe, Ostriker, Parker, Rhee, Richard, Sanderson, Schramm, Sheth, Smith, Strazzullo, Tissera, Umetsu, Vikhlinin, Wang   +92 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source