Results 151 to 160 of about 3,540 (186)

Polo-like kinase 4: A molecular linchpin in cancer and its management. [PDF]

iScience
Muntaqua D, Chhabra G, Anaya Aldrete KB, Ahmad N.   +3 more
europepmc   +1 more source

Polo-like kinase 4 (PLK4) as a therapeutic target in breast cancer. [PDF]

Carcinogenesis
Parsyan A, Athwal H, Bhat V, Allan AL.
europepmc   +1 more source

Meiotic progression in multinuclear mouse spermatocytes without the spindle pole clustering motor protein KIFC1 or cytokinesis forms single-cell late-stage spermatids. [PDF]

Sci Rep
Simerly C, Hartnett C, Zyhowski A, Robertson E, Harrison C, Cho IK, Easley C, Schatten G.   +7 more
europepmc   +1 more source

The A-C linker controls centriole structural integrity and duplication. [PDF]

Nat Commun
Bournonville L, Laporte MH, Borgers S, Guichard P, Hamel V.   +4 more
europepmc   +1 more source

Reviewer #3 (Public Review): CEP44 is required for maintaining centriole duplication and spindle integrity

Donghui Zhang, Wenlu Wei, Xiaopeng Zou, Hui Meng, Fangyuan Li, Minjun Yao, Junling Teng, Ning Huang, Jianguo Chen   +8 more
openalex   +1 more source

14-3-3ε inhibits premature centriole disengagement by inhibiting the activity of Plk1 and separase. [PDF]

J Cell Sci
Jaiswal MA, Karn A, Das A, Kumari A, Tiwari S, Dalal SN.   +5 more
europepmc   +1 more source

Investigating the maturation and duplication of mammalian centrioles.

, 2016
Faragher, A, Lange, B, Gull, K
openaire   +1 more source

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Emerging insights into symmetry breaking in centriole duplication: updated view on centriole duplication theory

Current Opinion in Structural Biology, 2021
Centriole duplication occurs once per cell cycle. Since only a single daughter centriole is assembled adjacent to each mother centriole, symmetry around the mother centriole must be broken in the process of centriole duplication. Recent studies have established that Plk4, a master kinase for centriole duplication, can self-assemble into condensates ...
Shohei, Yamamoto, Daiju, Kitagawa
openaire   +2 more sources

The Polo kinase Plk4 functions in centriole duplication

Nature Cell Biology, 2005
The human Polo-like kinase 1 (PLK1) and its functional homologues that are present in other eukaryotes have multiple, crucial roles in meiotic and mitotic cell division. By contrast, the functions of other mammalian Polo family members remain largely unknown.
Christopher J Wilkinson, Erich A Nigg
exaly   +4 more sources

The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries [PDF]

Nature Cell Biology, 2011
Centrosomes are microtubule-organizing centres of animal cells. They influence the morphology of the microtubule cytoskeleton, function as the base for the primary cilium and serve as a nexus for important signalling pathways. At the core of a typical centrosome are two cylindrical microtubule-based structures termed centrioles, which recruit a matrix ...
Erich A Nigg, Tim P Stearns
exaly   +4 more sources