Results 121 to 130 of about 55,531 (223)

M18BP1 valency and a distributed interaction footprint determine epigenetic centromere specification in humans. [PDF]

EMBO J
Walstein K, Hill L, Vogt D, Oberste-Lehn L, Janning P, Vetter IR, Pan D, Musacchio A.   +7 more
europepmc   +1 more source

Pitfalls and missing links in current understanding of 4D genomes

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The spatial and temporal organization of the genome—collectively termed the 4D genome—is pivotal for regulating gene expression, maintaining genome stability, and guiding development. The convergence of chromosome conformation capture technologies, super‐resolution microscopy, and single‐cell epigenomics has transformed our understanding of ...
Michael Q. Zhang
wiley   +1 more source

Protective Effect of LGG From Lophatherum Gracile Brongn. on Alcohol‐Injured HepG2 Cells and Exploration of Potential Mechanism

eFood, Volume 7, Issue 2, April 2026.
LGG was separated from L. gracile and its hepatoprotective effect was investigated. LGG significantly reduced the mortality, ROS and MDA content in alcohol‐injured liver cells. LGG up‐regulated 156 mRNAs (63 miRNAs) and down‐regulated 1529 mRNAs (35 miRNAs).
Yi‐Long Ma, Xin Guo, Zheng‐Fang Wu, Qian‐Lan Wu, Jing Li, Tian‐Le Mao, Zhi Li, Ya‐Fang Shang, Kiran Thakur, Zhao‐Jun Wei   +9 more
wiley   +1 more source

CentriVision: An integrated platform for multiscale centromere analysis in plants. [PDF]

Plant Commun
Lan MF, Wang XY, Zhang XC.
europepmc   +1 more source

Scleredema Associated With IgG/κ Monoclonal Gammopathy of Clinical Significance Successfully Treated With Daratumumab Monotherapy: A Case Report

eJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Background Cutaneous monoclonal gammopathy of clinical significance (MGCS) is rare and may present with scleredema‐like fibrosing skin disease. Case A 59‐year‐old man developed progressive induration of the upper body. Laboratory studies revealed an IgG/κ monoclonal protein, and skin biopsy showed dermal thickening with mucin deposition.
Davide Marcolongo, Alessandra Bressan, Elisabetta Zanatta, Mauro S. A. Alaibac, Ilaria Gianesello, Gianni Binotto, Laura Pavan, Angelo Paolo Dei Tos, Livio Trentin, Fabrizio Vianello   +9 more
wiley   +1 more source

Progressive coevolution of the yeast centromere and kinetochore. [PDF]

Nature
Helsen J, Ramachandran K, Sherlock G, Dey G.   +3 more
europepmc   +1 more source

Transition From Juvenile Dermatomyositis to Spondyloarthritis: A Novel Overlapping Inflammatory Phenotype

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective Juvenile dermatomyositis (JDM) is a rare childhood inflammatory myopathy, whereas spondyloarthritis (SpA) is an inflammatory arthropathy characterized by enthesitis and peripheral or axial involvement. We describe a series of patients diagnosed with JDM in childhood who later fulfilled classification criteria for SpA, a sequential phenotype ...
Austen Grooms, Ioannis Karageorgiou, Kerry Mychaliska, James Birmingham   +3 more
wiley   +1 more source

Genetic diversity and architectural dynamics of soybean centromeres. [PDF]

Genome Biol
Huang Y, Guan E, Song S, Koo DH, Schmidt MA, Su H, Chen C, Zhang J.   +7 more
europepmc   +1 more source

Distinct by Design: Unraveling the Unique Clinical and Transcriptomic Identity of Juvenile Scleromyositis Overlap Compared to Juvenile Systemic Sclerosis and Juvenile Dermatomyositis: Implications for Care and Pathogenesis

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective To characterize clinical and transcriptomic differences in juvenile scleromyositis overlap (jOverlap) compared to juvenile systemic sclerosis (jSSc) and juvenile dermatomyositis (JDM), focusing on autoantibody profiles, organ involvement, treatment, and peripheral blood gene expression.
Amanda D. Robinson, Clare E. Pain, Gabrielle A. Morgan, Anwesha Sanyal, Srilakshmi Chaparala, Lauren M. Pachman, Kathryn S. Torok   +6 more
wiley   +1 more source

Mild Photoperiod and Temperature Fluctuations Elicit Tissue‐Specific DNA Methylation Changes in Arabidopsis

Plant, Cell &Environment, EarlyView.
Ji Hoon Rhee, Hyogi Kim, Hyodong Lee, Yunji Jeon, Yeonhee Choi   +4 more
wiley   +1 more source