Results 131 to 140 of about 92,899 (342)

Centromere location in Arabidopsis is unaltered by extreme divergence in CENH3 protein sequence

open access: yesGenome Research, 2017
During cell division, spindle fibers attach to chromosomes at centromeres. The DNA sequence at regional centromeres is fast evolving with no conserved genetic signature for centromere identity.
Shamoni Maheshwari   +4 more
semanticscholar   +1 more source

Determining the function of histone modifications and transcription during centromere establishment in Caenorhabditis elegans

open access: yes, 2018
The centromere is a chromosomal region specialized for directing chromosome segregation. The kinetochore assembles on the centromere, attaching microtubules to chromosomes in mitosis.
Zhu, J, Yuen, KWY
core  

Centromere proteins CENP-C and CAL1 functionally interact in meiosis for centromere clustering, pairing, and chromosome segregation

open access: yes, 2013
Meiotic chromosome segregation involves pairing and segregation of homologous chromosomes in the first division and segregation of sister chromatids in the second division.
Orr-Weaver, Terry, Unhavaithaya, Yingdee
core   +1 more source

Comparative Satellitomics in Arowanas (Telostei, Osteoglossiformes) Sheds Light on the Evolution of Ancient Satellite DNAs

open access: yesIntegrative Zoology, EarlyView.
This work focused on arowana fishes (Teleostei, Osteoglossiformes) as a model; their widespread intercontinental distribution and basal phylogenetic position within Teleostei make them a compelling model for evolutionary research, especially in the realm of satDNA molecular evolution. Through the integration of genomic and chromosomal data, we analyzed
Fernando Henrique Santos de Souza   +9 more
wiley   +1 more source

α satellite DNA variation and function of the human centromere

open access: yesThe Nucleus, 2017
Genomic variation is a source of functional diversity that is typically studied in genic and non-coding regulatory regions. However, the extent of variation within noncoding portions of the human genome, particularly highly repetitive regions, and the ...
Lori L. Sullivan   +2 more
semanticscholar   +1 more source

Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy

open access: yesAndrology, EarlyView.
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby   +10 more
wiley   +1 more source

Centromere and kinetochore gene misexpression predicts cancer patient survival and response to radiotherapy and chemotherapy

open access: yesNature Communications, 2016
Chromosomal instability (CIN) is a hallmark of cancer that contributes to tumour heterogeneity and other malignant properties. Aberrant centromere and kinetochore function causes CIN through chromosome missegregation, leading to aneuploidy ...
Weiguo Zhang   +6 more
semanticscholar   +1 more source

Centromeres [PDF]

open access: yesCurrent Biology, 2001
Allshire, Robin, Pidoux, Alison
openaire   +2 more sources

Video_1_Only the Rye Derived Part of the 1BL/1RS Hybrid Centromere Incorporates CENH3 of Wheat.MP4

open access: yes, 2021
The precise assembly of the kinetochore complex at the centromere is epigenetically determined by substituting histone H3 with the centromere-specific histone H3 variant CENH3 in centromeric nucleosomes.
Veit Schubert (254739)   +2 more
core   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

open access: yesAndrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz   +12 more
wiley   +1 more source

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