Results 101 to 110 of about 92,899 (342)

Quiescent cells actively replenish CENP-A nucleosomes to maintain centromere identity and proliferative potential

open access: yesbioRxiv, 2018
Centromeres provide a robust model for epigenetic inheritance as they are specified by sequence-independent mechanisms involving the histone H3-variant CENP-A.
S. Z. Swartz   +7 more
semanticscholar   +1 more source

Microtubule Destabilizing Kinesins: A Historical Perspective and Thoughts for the Future

open access: yesCytoskeleton, EarlyView.
ABSTRACT The microtubule cytoskeleton plays critical roles in multiple cellular processes such as mitotic spindle assembly and chromosome segregation. Cells contain a number of microtubule‐associated proteins that regulate microtubule dynamics both temporally and spatially in cells. The microtubule depolymerizing kinesins include members of the Kinesin‐
Claire E. Walczak
wiley   +1 more source

The Ins and Outs of Aurora B Inner Centromere Localization

open access: yesFront. Cell Dev. Biol., 2017
Error-free chromosome segregation is essential for the maintenance of genomic integrity during cell division. Aurora B, the enzymatic subunit of the Chromosomal Passenger Complex (CPC), plays a crucial role in this process.
Sanne Hindriksen, S. Lens, M. A. Hadders
semanticscholar   +1 more source

Centromere-associated molecular events contribute to species diversification in fungal pathogens.

open access: yes
(a–e) Various molecular events involving centromeres leading to species diversification are depicted, with examples found among the fungal pathogens. (f) An evolutionary model for chromosomal fusion and centromere inactivation in the Malassezia species ...
Kaustuv Sanyal (169834)   +2 more
core   +1 more source

Cell cycle dynamics of histone variants at the centromere, a model for chromosomal landmarks

open access: yes, 2011
International audienceClassical heterochromatin chromosomal landmarks, such as centromeres and telomeres, are characterized by specific chromatin signatures. Among these, the incorporation of histone variants has recently emerged as an important feature.
Montes de Oca, Rocío   +5 more
core   +1 more source

CENPW (centromere protein W) [PDF]

open access: yes, 2014
Review on CENPW (centromere protein W), with data on DNA, on the protein encoded, and where the gene is ...
Jeon, S, Lee, S
core   +1 more source

Polymorphic STRs represent unique genetic signals beyond SNPs associated with climate adaptation in Marchantia polymorpha

open access: yesiMetaOmics, EarlyView.
Natural populations of Marchantia polymorpha sampled across contrasting climatic regions show clear geographic differentiation between Europe and Japan based on polymorphic short tandem repeat (STR) variation. Genome‐wide association (GWAS) analyses identified pSTR loci whose repeat‐length variation tracks temperature‐related WorldClim variables.
Shuangyang Wu   +4 more
wiley   +1 more source

Simulation and Quantitative Analysis of Spatial Centromere Distribution Patterns

open access: yesCells
A prominent feature of eukaryotic chromosomes are centromeres, which are specialized regions of repetitive DNA required for faithful chromosome segregation during cell division.
Adib Keikhosravi   +3 more
doaj   +1 more source

Temporal characterization of homology-independent centromere coupling in meiotic prophase.

open access: yesPLoS ONE, 2010
BackgroundOver the past thirty years several reports of the pairing or association of non-homologous centromeres during meiotic prophase have appeared in the literature.
David Obeso, Dean S Dawson
doaj   +1 more source

Cellular and Molecular Mechanisms of Centromere Drive

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 2018
The asymmetric outcome of female meiosis I, whereby an entire set of chromosomes are discarded into a polar body, presents an opportunity for selfish genetic elements to cheat the process and disproportionately segregate to the egg.
M. Lampson, B. E. Black
semanticscholar   +1 more source

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