Results 91 to 100 of about 68,825 (297)

Polymorphic STRs represent unique genetic signals beyond SNPs associated with climate adaptation in Marchantia polymorpha

iMetaOmics, EarlyView.
Natural populations of Marchantia polymorpha sampled across contrasting climatic regions show clear geographic differentiation between Europe and Japan based on polymorphic short tandem repeat (STR) variation. Genome‐wide association (GWAS) analyses identified pSTR loci whose repeat‐length variation tracks temperature‐related WorldClim variables.
Shuangyang Wu, Shenghan Gao, Sen Wang, Martin Lascoux, Hao Yu   +4 more
wiley   +1 more source

Determining the function of histone modifications and transcription during centromere establishment in Caenorhabditis elegans

, 2018
The centromere is a chromosomal region specialized for directing chromosome segregation. The kinetochore assembles on the centromere, attaching microtubules to chromosomes in mitosis.
Zhu, J, Yuen, KWY
core  

Centromere-stabilized aneuploid states leads to antifungal drug resistance.

(a) A table summarizing the outcome of karyotype alterations induced by different antifungal drugs in various pathogenic fungi. (b) Stable aneuploid states existing as whole chromosomes or supernumerary chromosomes arising from the core chromosomes.
Kaustuv Sanyal (169834), Md. Hashim Reza (18271476), Aswathy Narayanan (9903642)   +2 more
core   +1 more source

Routine MDM2 FISH Testing and Preoperative Biopsy Reduces Recurrence Rate of Atypical Lipomatous Tumours

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Although MDM2 FISH test has been increasingly used to differentiate ALT and benign lipomatous tumours, its impact on clinical outcome remains underexplored. This study investigated whether routine MDM2 FISH testing on preoperative biopsy is associated with a reduction in the recurrence risk of ALT.
Samuel O. H. Ching, Anderson S. M. Leung, Raymond C. H. Yau, Albert Y. L. Lam, Tony W. H. Shek, Maximus C. F. Yeung   +5 more
wiley   +1 more source

Centromeres [PDF]

Current Biology, 2001
Allshire, Robin, Pidoux, Alison
openaire   +2 more sources

Genetic manipulation of centromere function. [PDF]

, 1987
A conditional centromere was constructed in Saccharomyces cerevisiae by placing the centromere of chromosome III immediately downstream from the inducible GAL1 promoter from S. cerevisiae.
Bloom, K, Hill, A
core   +1 more source

Nephrogenic Systemic Fibrosis: A Rare Contemporary Case After a Decade of Declining Incidence

JEADV Clinical Practice, EarlyView.
ABSTRACT Nephrogenic systemic fibrosis (NSF) is a rare fibrosing disorder associated with exposure to gadolinium‐based contrast agents in patients with renal impairment. Although its incidence has markedly declined since the restriction of high‐risk linear gadolinium agents, sporadic cases may still occur.
Marta Sánchez Díaz, Alberto Andamoyo Castañeda, Pedro José Navarro Guillamón, Elena Gallego Domínguez, Jorge Alonso Suárez Pérez, Enrique Herrera Acosta   +5 more
wiley   +1 more source

PBRM1 directs PBAF to pericentromeres and protects centromere integrity

Nature Communications
The specialised structure of the centromere is critical for effective chromosome segregation, but its repetitive nature makes it vulnerable to rearrangements.
Karen A. Lane, Alison Harrod, Lillian Wu, Theodoros I. Roumeliotis, Hugang Feng, Shane Foo, Katheryn A. G. Begg, Federica Schiavoni, Noa Amin, Frank T. Zenke, Alan A. Melcher, Jyoti S. Choudhary, Jessica A. Downs   +12 more
doaj   +1 more source

Epigenetic regulation of centromere function

, 2020
The centromere is a specialized region on the chromosome that directs equal chromosome segregation. Centromeres are usually not defined by DNA sequences alone.
Lee, BCH, Wong, CYY, Yuen, KWY
core   +1 more source

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu, Xiao‐Bo Wan, Yong‐Shun Liang, Tian Lan, Hao Liang   +4 more
wiley   +1 more source