Results 91 to 100 of about 87,751 (339)

Temporal characterization of homology-independent centromere coupling in meiotic prophase.

open access: yesPLoS ONE, 2010
BackgroundOver the past thirty years several reports of the pairing or association of non-homologous centromeres during meiotic prophase have appeared in the literature.
David Obeso, Dean S Dawson
doaj   +1 more source

Centromere Biology: Transcription Goes on Stage

open access: yesMolecular and Cellular Biology, 2018
Accurate chromosome segregation is a fundamental process in cell biology. During mitosis, chromosomes are segregated into daughter cells through interactions between centromeres and microtubules in the mitotic spindle.
C. Perea-Resa, Michael D. Blower
semanticscholar   +1 more source

Centromere detection.

open access: yes, 2023
Centromere detection using CentO sequences and CentO-based centromere correction distribution for rice chromosomes 3, 7 and 9. The plots on the left show the count of CentO alignments in 100 kb windows for the reference sequence in blue and the query ...
Mauricio Peñuela (7138847)   +6 more
core   +1 more source

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

open access: yesAdvanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang   +19 more
wiley   +1 more source

Duplication of centromeric histone H3 (HTR12) gene in Arabidopsis halleri and A-lyrata, plant species with multiple centromeric satellite sequences [PDF]

open access: yes, 2006
Arabidopsis halleri and lyrata have three different major centromeric satellite sequences, a unique finding for a diploid Arabidopsis species. Since centromeric histones coevolve with centromeric satellites, these proteins would be predicted to show ...
A. Kawabe   +5 more
core   +1 more source

De Novo Complex Genomic Rearrangement Spanning 2q31.1 in a Proband With Congenital Malformations: Genotype–Phenotype Correlation and Development of a CGR Detection Pipeline

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The 2q31 region is commonly associated with pathogenic alleles of the HOXD cluster leading to various clinical phenotypes related to skeletal development. We present a proband with tetralogy of Fallot and multiple congenital anomalies. Genomic variant screening including an in‐house CGR detection pipeline pairing genome sequencing (GS ...
Katherine Helle   +10 more
wiley   +1 more source

Simulation and Quantitative Analysis of Spatial Centromere Distribution Patterns

open access: yesCells
A prominent feature of eukaryotic chromosomes are centromeres, which are specialized regions of repetitive DNA required for faithful chromosome segregation during cell division.
Adib Keikhosravi   +3 more
doaj   +1 more source

Cellular and Molecular Mechanisms of Centromere Drive

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 2018
The asymmetric outcome of female meiosis I, whereby an entire set of chromosomes are discarded into a polar body, presents an opportunity for selfish genetic elements to cheat the process and disproportionately segregate to the egg.
M. Lampson, B. E. Black
semanticscholar   +1 more source

Equine models in translational medicine: A comparative approach to human health

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh   +1 more
wiley   +1 more source

Cell cycle dynamics of histone variants at the centromere, a model for chromosomal landmarks

open access: yes, 2011
International audienceClassical heterochromatin chromosomal landmarks, such as centromeres and telomeres, are characterized by specific chromatin signatures. Among these, the incorporation of histone variants has recently emerged as an important feature.
Montes de Oca, Rocío   +5 more
core   +1 more source

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