Results 151 to 160 of about 26,352 (303)

Consensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl, J. Christopher Corton, Henghong Li, Jiri Aubrecht, Scott S. Auerbach, Florian Caiment, Tatyana Y. Doktorova, Yurika Fujita, Danyel Jennen, Naoki Koyama, Matthew J. Meier, Roman Mezencev, Leslie Recio, Takayoshi Suzuki, Carole L. Yauk   +14 more
wiley   +1 more source

Genome architecture and diverged selection shaping pattern of genomic differentiation in wild barley

Plant Biotechnology Journal, Volume 21, Issue 1, Page 46-62, January 2023., 2023
Summary Divergent selection of populations in contrasting environments leads to functional genomic divergence. However, the genomic architecture underlying heterogeneous genomic differentiation remains poorly understood. Here, we de novo assembled two high‐quality wild barley (Hordeum spontaneum K. Koch) genomes and examined genomic differentiation and
Wenying Zhang, Cong Tan, Haifei Hu, Rui Pan, Yuhui Xiao, Kai Ouyang, Gaofeng Zhou, Yong Jia, Xiao‐Qi Zhang, Camilla Beate Hill, Penghao Wang, Brett Chapman, Yong Han, Le Xu, Yanhao Xu, Tefera Angessa, Hao Luo, Sharon Westcott, Darshan Sharma, Eviatar Nevo, Roberto A. Barrero, Matthew I. Bellgard, Tianhua He, Xiaohai Tian, Chengdao Li   +24 more
wiley   +1 more source

The asexual genome of Drosophila [PDF]

arXiv, 2017
The rate of recombination affects the mode of molecular evolution. In high-recombining sequence, the targets of selection are individual genetic loci; under low recombination, selection collectively acts on large, genetically linked genomic segments. Selection under linkage can induce clonal interference, a specific mode of evolution by competition of ...
arxiv  

Identification of a UDP‐glucosyltransferase conferring deoxynivalenol resistance in Aegilops tauschii and wheat

Plant Biotechnology Journal, Volume 21, Issue 1, Page 109-121, January 2023., 2023
Summary Aegilops tauschii is the diploid progenitor of the wheat D subgenome and a valuable resource for wheat breeding, yet, genetic analysis of resistance against Fusarium head blight (FHB) and the major Fusarium mycotoxin deoxynivalenol (DON) is lacking. We treated a panel of 147 Ae. tauschii accessions with either Fusarium graminearum spores or DON
Rizky Pasthika Kirana, Kumar Gaurav, Sanu Arora, Gerlinde Wiesenberger, Maria Doppler, Sebastian Michel, Simone Zimmerl, Magdalena Matic, Chinedu E. Eze, Mukesh Kumar, Ajla Topuz, Marc Lemmens, Rainer Schuhmacher, Gerhard Adam, Brande B. H. Wulff, Hermann Buerstmayr, Barbara Steiner   +16 more
wiley   +1 more source

What makes a centromere?

Experimental Cell Research, 2020
P. Talbert, S. Henikoff
semanticscholar   +1 more source

STUDIES OF A TELOCENTRIC CHROMOSOME IN MAIZE WITH REFERENCE TO THE STABILITY OF ITS CENTROMERE [PDF]

, 1940
M. M. Rhoades
openalex   +1 more source

Time‐ordering japonica/geng genomes analysis indicates the importance of large structural variants in rice breeding

Plant Biotechnology Journal, Volume 21, Issue 1, Page 202-218, January 2023., 2023
Summary Temperate japonica/geng (GJ) rice yield has significantly improved due to intensive breeding efforts, dramatically enhancing global food security. However, little is known about the underlying genomic structural variations (SVs) responsible for this improvement.
Yu Wang, Fengcheng Li, Fan Zhang, Lian Wu, Na Xu, Qi Sun, Hao Chen, Zhiwen Yu, Jiahao Lu, Kai Jiang, Xiaoche Wang, Siyu Wen, Yao Zhou, Hui Zhao, Qian Jiang, Jiahong Wang, Ruizong Jia, Jian Sun, Liang Tang, Hai Xu, Wei Hu, Zhengjin Xu, Wenfu Chen, Anping Guo, Quan Xu   +24 more
wiley   +1 more source

CENH3 morphogenesis reveals dynamic centromere associations during synaptonemal complex formation and the progression through male meiosis in hexaploid wheat

The Plant Journal, 2017
Summary During meiosis, centromeres in some species undergo a series of associations, but the processes and progression to homologous pairing is still a matter of debate.
A. Sepsi, J. Higgins, J. Heslop-Harrison, T. Schwarzacher   +3 more
semanticscholar   +1 more source

Quadruple Structure of the Centromere [PDF]

, 1950
J. H. Tjio, ALBERT LEVAN
openalex   +1 more source

Mechanisms of enhancer‐driven oncogene activation

International Journal of Cancer, EarlyView.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend, Ruud Delwel, Dorien Pastoors   +2 more
wiley   +1 more source