Results 221 to 230 of about 59,497 (285)

Structural basis of product recognition by Mycobacterium tuberculosis fatty acid synthase

open access: yesProtein Science, Volume 35, Issue 1, January 2026.
Abstract Microbial iterative fatty acid synthases (FAS) are versatile multienzymes under scrutiny for their potential as anti‐infectious targets and their biotechnological applications. They produce saturated fatty acids with defined chain length and release them as coenzyme A‐conjugates.
Elnaz Khalili Samani   +4 more
wiley   +1 more source

Dual Role of Topoisomerase II in Centromere Resolution and Aurora B Activity

open access: gold, 2008
Paula A. Coelho   +5 more
openalex   +2 more sources

Isolated Anti‐SS‐A Antibody Seropositivity as a Poor Prognostic Factor in Systemic Sclerosis: Insights From a Cohort of 307 Cases

open access: yesThe Journal of Dermatology, Volume 53, Issue 1, Page 41-53, January 2026.
ABSTRACT Systemic sclerosis is an autoimmune disease characterized by vasculopathy, fibrosis, and immune dysregulation. Anti‐SS‐A antibodies (anti‐SSA) have been reported to confer severe clinical manifestations in some Western and Japanese cohorts. We aimed to determine whether anti‐SSA seropositivity affects clinical outcomes in Japanese patients. We
Nana Ishida   +4 more
wiley   +1 more source

PolySUMOylation of PCNA and Rad52 restricts centromeric recombination in fission yeast. [PDF]

open access: yesNat Commun
Markowska K   +8 more
europepmc   +1 more source

High‐Quality Genome Assembly of Diplocarpon coronariae Unveils LTR Retrotransposon‐Driven Structural Dynamics in Fungi Evolution

open access: yesMolecular Ecology Resources, Volume 26, Issue 1, January 2026.
ABSTRACT Long terminal repeat retrotransposons (LTR‐RTs) are recognised as a significant evolutionary force capable of shaping the structure and function of the genomes in eukaryotes, including animals, plants, and fungi. However, much remains largely unknown about how LTR‐RTs influence the evolution of fungi at the chromosomal level.
Chengyu Gao   +4 more
wiley   +1 more source

Complete genome assemblies of two mouse subspecies reveal structural diversity of telomeres and centromeres. [PDF]

open access: yesNat Genet
Francis BA   +17 more
europepmc   +1 more source

Oocyte Age‐Dependent DNA Damage Can Be Reverted by the DNA Repair Competent Karyoplasm of Young Oocytes

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
As females age, oocyte chromosomal aberrations and DNA damage increase in frequency; this condition is believed to be irreversible. By exposing the aged oocyte nuclei to nuclear factors from young oocytes, the negative effects can be effectively suppressed, restoring their developmental competence. ABSTRACT Mammalian fully grown oocytes are believed to
Nataliia Dudko   +8 more
wiley   +1 more source

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