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Sister chromatid exchange in the centromere and centromeric area
Human Genetics, 1983Central and peripheral sister chromatid exchanges (SCE) were evaluated separately in human phytohemagglutinin (PHA)-stimulated lymphocytes after culture for 72 h in 5-bromodeoxyuridine (BrdU) containing medium. At the same time, the length of chromosome No.
R, Becher, A A, Sandberg
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Yeast, 1987
Significant progress has been made toward understanding the roles played by conserved centromere DNA sequences in both mitotic and meiotic chromosome segregation. We are just beginning to formulate a picture of what a yeast kinetochore actually looks like and what components other than CEN DNA are necessary for function.
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Significant progress has been made toward understanding the roles played by conserved centromere DNA sequences in both mitotic and meiotic chromosome segregation. We are just beginning to formulate a picture of what a yeast kinetochore actually looks like and what components other than CEN DNA are necessary for function.
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Current Opinion in Genetics & Development, 2007
At the foundation of all eukaryotic kinetochores is a unique histone variant, known as CenH3 (centromere histone H3). We are starting to identify the histone chaperones responsible for CenH3 deposition at centromere DNA, and the mechanisms that restrict CenH3 from chromosome arms.
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At the foundation of all eukaryotic kinetochores is a unique histone variant, known as CenH3 (centromere histone H3). We are starting to identify the histone chaperones responsible for CenH3 deposition at centromere DNA, and the mechanisms that restrict CenH3 from chromosome arms.
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Chromosoma, 1989
Human anti-centromere sera from scleroderma patients were used to detect centromere antigens of mouse fibroblast cells. An Mr = 59,000 centromere protein was localized exclusively on mitotic chromosomes. The association of this protein with the mitotic chromosomes proved to be DNase I sensitive.
G, Hadlaczky +3 more
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Human anti-centromere sera from scleroderma patients were used to detect centromere antigens of mouse fibroblast cells. An Mr = 59,000 centromere protein was localized exclusively on mitotic chromosomes. The association of this protein with the mitotic chromosomes proved to be DNase I sensitive.
G, Hadlaczky +3 more
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1997
Abstract The centromere is an essential structure on all eukaryotic chromosomes that allows the equipartition of chromosomes during mitotic and meiotic cell divisions. Since its cytogenetic recognition as a constructed part of a chromosome many decades ago, great advance has been made on our understanding of this intriguing structure,
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Abstract The centromere is an essential structure on all eukaryotic chromosomes that allows the equipartition of chromosomes during mitotic and meiotic cell divisions. Since its cytogenetic recognition as a constructed part of a chromosome many decades ago, great advance has been made on our understanding of this intriguing structure,
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