Results 1 to 10 of about 3,046,785 (263)
Bisphenol A and its analogues disrupt centrosome cycle and microtubule dynamics in prostate cancer. [PDF]
Endocr Relat Cancer, 2017 S. Ho +4 more
semanticscholar +3 more sources
Cell Cycle-Dependent Dynamics of the Golgi-Centrosome Association in Motile Cells [PDF]
Cells, 2020 Here, we characterize spatial distribution of the Golgi complex in human cells. In contrast to the prevailing view that the Golgi compactly surrounds the centrosome throughout interphase, we observe characteristic differences in the morphology of Golgi ...
Keyada Frye +6 more
semanticscholar +4 more sources
A Novel Bipartite Centrosome Coordinates the Apicomplexan Cell Cycle
PLoS Biology, 2015 Apicomplexan parasites can change fundamental features of cell division during their life cycles, suspending cytokinesis when needed and changing proliferative scale in different hosts and tissues.
E. Suvorova +3 more
semanticscholar +4 more sources
The Cep192-organized aurora A-Plk1 cascade is essential for centrosome cycle and bipolar spindle assembly. [PDF]
Mol Cell, 2014 V. Joukov, J. Walter, A. De Nicolo
semanticscholar +3 more sources
Centrosome maturation - in tune with the cell cycle. [PDF]
Journal of Cell Science, 2022 Centrosomes are the main microtubule-organizing centres, playing essential roles in the organization of the cytoskeleton during interphase, and in the mitotic spindle, which controls chromosome segregation, during cell division.
José Blanco-Ameijeiras +2 more
semanticscholar +2 more sources
An updated view on the centrosome as a cell cycle regulator
Cell Division, 2022 The centrosome is a multifunctional organelle that is known primarily for its microtubule organising function. Centrosomal defects caused by changes in centrosomal structure or number have been associated with human diseases ranging from congenital ...
Muyang Lin, S. Xie, Kuan Yoow Chan
semanticscholar +2 more sources
Uncoordinated centrosome cycle underlies the instability of non-diploid somatic cells in mammals [PDF]
J Cell Biol, 2018 In animals, somatic cells are usually diploid and are unstable when haploid for unknown reasons. In this study, by comparing isogenic human cell lines with different ploidies, we found frequent centrosome loss specifically in the haploid state, which ...
Kan Yaguchi +7 more
semanticscholar +2 more sources
Regulation of the centrosome cycle [PDF]
Mol Cell Oncol, 2015 The centrosome, consisting of mother and daughter centrioles surrounded by the pericentriolar matrix (PCM), functions primarily as a microtubule organizing center (MTOC) in most animal cells.
Hiroki Fujita, Yuki Yoshino, N. Chiba
semanticscholar +2 more sources
Cell Division, 2011 Because centrosome amplification generates aneuploidy and since centrosome amplification is ubiquitous in human tumors, a strong case is made for centrosome amplification being a major force in tumor biogenesis.
M. Harrison +2 more
semanticscholar +3 more sources
Haematologica, 2023 DIS3 gene mutations occur in approximately 10% of patients with multiple myeloma (MM); furthermore, DIS3 expression can be affected by monosomy 13 and del(13q), found in roughly 40% of MM cases. Despite the high incidence of DIS3 mutations and deletions,
Vanessa K. Favasuli +19 more
doaj +3 more sources