Results 11 to 20 of about 3,046,785 (263)

Uncoupling of DNA Replication and Centrosome Duplication Cycles Is a Primary Cause of Haploid Instability in Mammalian Somatic Cells

Frontiers in Cell and Developmental Biology, 2020
Mammalian haploid somatic cells are unstable and prone to diploidize, but the cause of haploid instability remains largely unknown. Previously, we found that mammalian haploid somatic cells suffer chronic centrosome loss stemming from the uncoupling of ...
Koya Yoshizawa, Kan Yaguchi, Ryota Uehara, Ryota Uehara   +3 more
doaj   +2 more sources

Influenza Virus Induces Cholesterol-Enriched Endocytic Recycling Compartments for Budozone Formation via Cell Cycle-Independent Centrosome Maturation

PLoS Pathogens, 2015
Influenza virus particles are assembled at the plasma membrane in concert with incorporation of the virus genome, but the details of its spatio-temporal regulation are not understood.
Atsushi Kawaguchi, Mikako Hirohama, Yoshimi Harada, Suguru Osari, K. Nagata   +4 more
semanticscholar   +2 more sources

The connections of Wnt pathway components with cell cycle and centrosome: side effects or a hidden logic?

Critical reviews in biochemistry and molecular biology, 2017
V. Bryja, I. Červenka, L. Čajánek
semanticscholar   +3 more sources

TUFT1 regulates cancer progression by suppressing centrosome amplification and mitotic spindle multipolarity [PDF]

Cell Death and Disease
Centrosome amplification (CA) has been observed in various solid tumors and contributes to chromosomal instability (CIN) and poor clinical prognosis in patients with cancer. CA also inhibits cell proliferation by inducing cell-cycle arrest and cell death.
Shaojie Feng, Mengmeng Zhao, Donghui Zhang, Yan Zhang, Lingyuan Min, Xianqiang Liu, Huan Shi, Tianning Wang   +7 more
doaj   +2 more sources

PLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycle [PDF]

EMBO Journal, 2010
Jaerak Chang, Onur Çizmecioğlu, I. Hoffmann, K. Rhee   +3 more
semanticscholar   +2 more sources

Matured hiPSC-derived cardiomyocytes possess dematuration plasticity [PDF]

Journal of Molecular and Cellular Cardiology Plus
Human induced Pluripotent Stem Cell-derived cardiomyocytes (hiPSC-CMs) are increasingly used to identify potential factors capable of inducing endogenous cardiomyocyte proliferation to regenerate the injured heart.
Fang Meng, Maxwell Kwok, Yen Chin Hui, Ruofan Wei, Alejandro Hidalgo-Gonzalez, Anna Walentinsson, Henrik Andersson, Frederik Adam Bjerre, Qing-Dong Wang, Ditte C. Andersen, Ellen Ngar-Yun Poon, Daniela Später, David C. Zebrowski   +12 more
doaj   +2 more sources

Bora, CEP192 and Cenexin activate different Plk1 pools and regulate distinct cell and centrosome cycle transitions [PDF]

Devashish Dwivedi, Clayton Luiz Borges, Daniela Harry, Luca Cirillo, Patrick Meraldi   +4 more
europepmc   +3 more sources

Cell cycle: Driving the centrosome cycle [PDF]

Current Biology, 1999
M. Winey
semanticscholar   +2 more sources

Duplication and Segregation of Centrosomes during Cell Division

Cells, 2022
During its division the cell must ensure the equal distribution of its genetic material in the two newly created cells, but it must also distribute organelles such as the Golgi apparatus, the mitochondria and the centrosome. DNA, the carrier of heredity,
Claude Prigent, Rustem Uzbekov
doaj   +1 more source

Functional Coordination among the Golgi Complex, the Centrosome and the Microtubule Cytoskeleton during the Cell Cycle

Cells, 2022
The Golgi complex of mammalian cells is organized in a ribbon-like structure often closely associated with the centrosome during interphase. Conversely, the Golgi complex assumes a fragmented and dispersed configuration away from the centrosome during ...
F. Mascanzoni, Roberta Iannitti, A. Colanzi   +2 more
semanticscholar   +1 more source