Results 41 to 50 of about 2,179 (236)

A robust genome and assembly with transcriptomic data from the striped scorpion, Centruroides vittatus

open access: yesbioRxiv, 2023
Scorpions, a seemingly primitive, stinging arthropod taxa, are known to exhibit marked diversity in their venom components. These venoms are known for their human pathology, but also important as models for therapeutic and drug development applications ...
T. Yamashita, D. Rhoads, Jeff Pummill
semanticscholar   +1 more source

Morphometric study and sexual dimorphism analyses in an Iranian population of Scorpio maurus (Arachnida: Scorpionidae)

open access: yesEcology and Evolution, Volume 11, Issue 22, Page 15630-15638, November 2021., 2021
Scorpio maurus was collected and evaluated for morphometric study and sexual dimorphism analyses for the first time in Iran. 53 morphological characters of 15 specimens of each sex of S. maurus were studied. Sexual dimorphism was observed in 21 morphological characters of S. maurus based on statistical analyses.
Parisa Soltan‐Alinejad   +4 more
wiley   +1 more source

Full Neutralization of Centruroides sculpturatus Scorpion Venom by Combining Two Human Antibody Fragments

open access: yesToxins, 2021
A fundamental issue of the characterization of single-chain variable fragments (scFvs), capable of neutralizing scorpion toxins, is their cross-neutralizing ability. This aspect is very important in Mexico because all scorpions dangerous to humans belong
Lidia Riaño-Umbarila   +5 more
doaj   +1 more source

Scorpion venom and its adaptive role against pathogens: a case study in Centruroides granosus Thorell, 1876 and Escherichia coli

open access: yesFrontiers in Arachnid Science, 2023
Scorpion venoms have been studied extensively, mostly aimed at applications for human health, with strong evidence of antimicrobial properties. However, ecological studies on the adaptive role of these antimicrobial properties have been mostly neglected.
Dumas Gálvez   +2 more
semanticscholar   +1 more source

Mass spectrometry‐based top‐down and bottom‐up approaches for proteomic analysis of the Moroccan Buthus occitanus scorpion venom

open access: yesFEBS Open Bio, Volume 11, Issue 7, Page 1867-1892, July 2021., 2021
Buthus occitanus scorpion possesses highly toxic venom. This article describes the first proteomic screening of the Moroccan B. occitanus venom. Our findings highlight the complexity and the toxin diversity of this venom. The most representative compounds are neurotoxins.
Khadija Daoudi   +8 more
wiley   +1 more source

Discovery of KV1.3 ion channel inhibitors: Medicinal chemistry approaches and challenges

open access: yesMedicinal Research Reviews, Volume 41, Issue 4, Page 2423-2473, July 2021., 2021
Abstract The KV1.3 voltage‐gated potassium ion channel is involved in many physiological processes both at the plasma membrane and in the mitochondria, chiefly in the immune and nervous systems. Therapeutic targeting KV1.3 with specific peptides and small molecule inhibitors shows great potential for treating cancers and autoimmune diseases, such as ...
Špela Gubič   +9 more
wiley   +1 more source

Sex‐Biased Gene Expression of Mesobuthus martensii Collected from Gansu Province, China, Reveals Their Different Therapeutic Potentials

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021
The scorpions, named Mesobuthus martensii, commonly called Quanxie (全蝎) in Chinese, have been widely used as one of the animal medicines for more than 1,000 years because of the strong toxicity of their venoms. Meanwhile, scorpions are sexually dimorphic in appearance, and many exhibit traits associated with sex‐biased gene expression, including ...
Songyu Gao   +11 more
wiley   +1 more source

Envenomation by Centruroides pococki scorpion with neuromuscular toxicity

open access: yesToxicon, 2021
Cases of human envenomation by Centruroides pococki are exceptionally reported in human. We report a Class III human envenomation by C. pococki in Guadeloupe, French West Indies, with neuromuscular toxicity that has never been described before. Symptoms resolved within a few hours, without the need for intravenous scorpion-specific antivenom.
Caré, Weniko   +6 more
openaire   +5 more sources

Characterization of Four Medically Important Toxins from Centruroides huichol Scorpion Venom and Its Neutralization by a Single Recombinant Antibody Fragment

open access: yesToxins, 2022
Centruroides huichol scorpion venom is lethal to mammals. Analysis of the venom allowed the characterization of four lethal toxins named Chui2, Chui3, Chui4, and Chui5.
Hugo Valencia-Martínez   +7 more
semanticscholar   +1 more source

Centruroides rileyi Sissom 1995

open access: yes, 2021
Published as part of Goodman, Aaron M., Prendini, Lorenzo, Francke, Oscar F. & Esposito, Lauren A., 2021, Systematic Revision Of The Arboreal Neotropical " Thorellii " Clade Of Centruroides Marx, 1890, Bark Scorpions (Buthidae C. L. Koch, 1837) With Descriptions Of Six New Species, pp.
Goodman, Aaron M.   +3 more
openaire   +1 more source

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